Katie Morris

A Brainwide Atlas of Synaptic Nanoarchitecture Across the Mouse Lifespan

The paper introduces NanoSYNMAP to map synaptic nanoarchitecture across the mouse lifespan, revealing how molecular proximity shapes synapse diversity.

Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching

This paper introduces a fluorescence de-quenching assay to study detergent-induced membrane remodeling, showing Triton X-100 causes morphological transitions at sub-critical concentrations.

3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain

This study uses 3D super-resolution microscopy to analyze PSD95 nanoarchitecture in the mouse brain, revealing diffuse supercomplexes outside synapses and distinct subtypes within synapses.

Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex.

The paper investigates the sequential replacement of PSD95 subunits in synaptic supercomplexes, finding that this process is slowest in the cortex where PSD95 has the longest lifetime.

Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

The paper tracks α-synuclein conformational changes in neurons and shows mitochondrial involvement in oligomerization and toxicity.