Author

Takeshi Kaizuka

University of EdinburghORCID 0000-0002-5253-1896Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Candace T. AdamsiD· 3 shared Edita BulovaiteiD· 3 shared Katie MorrisiD· 3 shared Mathew H. HorrocksiD· 3 shared Seth G. N. GrantiD· 3 shared Noboru H. KomiyamaiD· 2 shared Toru TakumiiD· 2 shared Alexander Spark· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Candace T. AdamsORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Brainwide Atlas of Synaptic Nanoarchitecture Across the Mouse Lifespan

Takeshi Kaizuka, Zhen Qiu, Edita Bulovaite, Katie Morris, Tianxiao Zhao, Candace Adams, Gabor Varga, Digin Dominic, Noboru H. Komiyama, Mathew H. Horrocks, Seth G. N. Grant

The paper introduces NanoSYNMAP to map synaptic nanoarchitecture across the mouse lifespan, revealing how molecular proximity shapes synapse diversity.

bioRxiv · Feb 18, 2026 · PreprintNeuroscience

3D super-resolution imaging of PSD95 reveals an abundance of diffuse protein supercomplexes in the mouse brain

Sam Daly, Edita Bulovaite, Anoushka Handa, Katie Morris, Leila Mureşan, Candace T. Adams, Takeshi Kaizuka, Alexandre Kitching, Alexander Spark, Gregory J. Chant, Kevin O’Holleran, Seth G. N. Grant, Mathew H. Horrocks, Steven F. Lee

This study uses 3D super-resolution microscopy to analyze PSD95 nanoarchitecture in the mouse brain, revealing diffuse supercomplexes outside synapses and distinct subtypes within synapses.

ACS Chemical Neuroscience · Dec 20, 2024Peer-reviewedBiophysics

Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex.

Katie Morris, Edita Bulovaite, Takeshi Kaizuka, Sebastian Schnorrenberg, Candace T. Adams, Noboru H. Komiyama, Lorena Mendive‐Tapia, Seth G. N. Grant, Mathew H. Horrocks

The paper investigates the sequential replacement of PSD95 subunits in synaptic supercomplexes, finding that this process is slowest in the cortex where PSD95 has the longest lifetime.

eLife · Nov 7, 2024Peer-reviewedNeuroscience

DRACC1, a major postsynaptic protein, regulates the condensation of postsynaptic proteins via liquid-liquid phase separation

Takeshi Kaizuka, Taisei Hirouchi, Takeo Saneyoshi, Yasunori Hayashi, Toru Takumi

The paper identifies DRACC1 as a novel synaptic protein that facilitates PSD protein assembly through liquid-liquid phase separation by analyzing 35 PSD proteome datasets.

bioRxiv · Jan 23, 2023 · PreprintNeuroscience

Developmental dynamics of the postsynaptic proteome to understand synaptic maturation and dysmaturation

Takeshi Kaizuka, Takehiro Suzuki, Noriyuki Kishi, Manfred W. Kilimann, Takehiko Ueyama, Masahiko Watanabe, Hideyuki Okano, Naoshi Dohmae, Toru Takumi

The paper examines changes in PSD protein composition across development in mice and primates, linking these changes to autism spectrum disorder.

bioRxiv · May 5, 2022 · PreprintNeuroscience