Vlad Zabrouskov

This study revisits resonance-excitation collision-induced dissociation (reCID) for DIA proteomics, showing it can achieve performance comparable to HCD with optimized settings and libraries.

This paper introduces a high-resolution multi-pass Astral analyzer mode for TMT proteomics, enabling 35-plex quantification with improved depth and precision.

Orbitrap Astral Zoom upgrades enable 270 Hz DIA scanning, identifying 7184 protein groups at 500 samples/day and >12,000 proteins from fractionated HEK293 in 2.7 h.

This paper evaluates a prototype Orbitrap Astral Zoom mass spectrometer for quantitative proteomics, showing improved performance in ion detection and quantitative precision compared to the standard Orbitrap Astral MS.

This study evaluates the Orbitrap Astral MS's sensitivity for single-cell proteomics, showing improved proteome coverage and quantitative accuracy in low-input samples.

The paper introduces a method using the Orbitrap Astral mass spectrometer with DIA to rapidly analyze phosphoproteomes, detecting over 80,000 phosphorylation sites in mice.

This study evaluates the Astral mass analyzer's performance in single-cell proteomics using DIA, showing improved proteome depth and quantitative precision for ultra-low input samples.

The paper introduces Narrow-window DIA, a fast proteomics method enabling high-throughput and comprehensive proteome analysis with high precision and accuracy.