Author

Justin Taylor

University of MiamiORCID 0000-0003-4407-6325Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

Aarthi Nivasini MaheshiD· 1 shared Adnan Kasim MookhtiariD· 1 shared Ahmed M. MamdouhiD· 1 shared Alexandre PuissantiD· 1 shared Anna Hudson· 1 shared Anna Lesley Kingham· 1 shared Ashish H Shah· 1 shared Bradley H. GampeliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

Aarthi Nivasini MaheshORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting an RNA Editor to Impede H3K27M+ Pediatric Gliomas

Christian Kieran Ramsoomair, Victoria Álvarez, Felipe Sarmiento, Manuela Aramburu Berckemeyer, Deepa Seetharam, Kajol Kalliecharan, Sreerag N. Moorkkannur, Jonathan Mitchell, Anna Hudson, Justin Taylor, Michele Ceccarelli, Defne Bayık, Oren Josh Becher, Rajeev Prabahakar, Scott M. Welford, , Ashish H Shah

This study identifies ADAR as a key mediator of immune evasion in H3K27M+ pediatric gliomas and shows that ATRA can induce ADAR degradation, enhancing antiviral responses and tumor immunogenicity.

bioRxiv · May 12, 2026 · PreprintCancer Biology

Co-targeting menin and LSD1 dismantles oncogenic programs and restores differentiation in MLL-rearranged AML

Mina Masoumeh Tayari, Helena Gomes Dos Santos, Felipe Beckedorff, Tulasigeri M. Totiger, Adnan Kasim Mookhtiar, Anna Lesley Kingham, Guilherme Miura Lavezzo, Glòria Mas Martín, Hsuan-Ting Huang, Efe Karaca, Daniel Bilbao, Justin Taylor, Ramin Shiekhattar, Justin M. Watts

This study identifies LSD1 as a cofactor of the menin-MLL-LEDGF complex and shows that combining menin and LSD1 inhibition effectively treats MLL-rearranged AML by dismantling oncogenic programs and promoting differentiation.

bioRxiv · Oct 13, 2025 · PreprintCancer Biology

BIRC5 dependency defines a targetable vulnerability in TP53 mutant acute myeloid leukemia

Ahmed M. Mamdouh, Fang Qi Lim, Yang Mi, Elyse A. Olesinski, Shaista Shabbir Jasdanwala, Xiao Xian Lin, Edward Ayoub, Jordan Yong Ming Tan, Karanpreet Singh Bhatia, Yichen Wang, Shradha Garnaik, Kunal Tomar, Valeriia Sapozhnikova, Cheryl Gek Teng Chan, Chuqi Wang, , Shruti Bhatt

This study identifies BIRC5 as a targetable vulnerability in TP53 mutant AML, showing that survivin/IAP inhibitors can overcome therapy resistance.

bioRxiv · May 17, 2025 · PreprintCancer Biology