Author

Tamaratare Ogu

Children's Medical CenterORCID 0009-0001-0654-6296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Feng CaiiD· 2 shared Ling CaiiD· 2 shared Phong T. NguyeniD· 2 shared Ralph J. DeBerardinisiD· 2 shared Varun SondhiiD· 2 shared Zheng WuiD· 2 shared Annie JeniD· 1 shared Dennis Dumesnil· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiochemistry

Feng CaiORCID

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2 papers

Recent·Most cited

UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism

Phong Nguyen, Zheng Wu, Dohun Kim, Tamaratare Ogu, Siyu Yin, Varun Sondhi, Feng Cai, Trevor S. Tippetts, Annie Jen, Evgenia Shishkova, Ling Cai, Dennis Dumesnil, Margaret B. Cervantes, Hongli Chen, Prashant Mishra, , Ralph J. DeBerardinis

This study identifies UFMylation of PDH as a regulator of mitochondrial metabolism, showing it enhances pyruvate oxidation and TCA cycle activity.

bioRxiv · Mar 18, 2026 · PreprintBiochemistry

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT

Zheng Wu, Phong T. Nguyen, Varun Sondhi, Run-Wen Yao, Zhifang Lu, Tao Dai, Jui‐Chung Chiang, Feng Cai, Imani M. Williams, Eliot B. Blatt, Zeng‐Fu Shang, Ling Cai, Jing Zhang, Mya D. Moore, Islam Alshamleh, , Ralph J. DeBerardinis

This study identifies NUDT5 as a regulator of purine metabolism and thiopurine sensitivity by interacting with PPAT, independent of its known enzymatic activity.

Science · Nov 6, 2025Peer-reviewedBiochemistry