Advanced MRI Techniques and Applications

Temporal dynamics of GABA and Glx in the visual cortex

The paper uses MRS data to analyze temporal dynamics of GABA+ and Glx in visual cortex, finding opposite drifts and predictive relationships between the two neurometabolites.

Comparison of BOLD and CBV using 3D EPI and 3D GRASE for cortical layer fMRI at 7T.

This study compares CBV and BOLD imaging techniques for cortical layer fMRI, finding both offer similar specificity and sensitivity for mesoscopic imaging.

Automated characterization of noise distributions in diffusion MRI data

This paper introduces automated methods to estimate noise distributions in diffusion MRI data using Gamma distribution moments and maximum likelihood, showing improved accuracy over Rician assumptions.

Analysis of task-based functional MRI data preprocessed with fMRIPrep

This paper introduces fMRIPrep, a tool for preprocessing task-based fMRI data, and demonstrates its integration into a workflow for statistical analysis.

ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies

ExploreASL provides a standardized image processing pipeline for multi-center ASL MRI studies, improving reproducibility and enabling group-level statistical analysis across diverse clinical populations.

Head motion during fMRI tasks is reduced in children and adults if participants take breaks

This study shows that splitting fMRI data acquisition into multiple sessions reduces head motion in children and breaks reduce motion in adults, but motion still increases over time in both groups.

Physiological Gaussian Process Priors for the Hemodynamics in fMRI Analysis

This paper introduces a Bayesian model for fMRI analysis that uses Gaussian process priors to estimate brain activity and hemodynamics without assuming a linear time-invariant system.

Multiband acceleration can provide moderate improvements in single-subject voxel-wise statistics in block-design task-based fMRI

This study shows that MB4 acceleration improves single-subject voxel-wise statistics in fMRI, with moderate effect sizes in the action observation network, but may over-penalize temporal autocorrelation.

Differential effects of aquaporin-4 channel inhibition on BOLD fMRI and Diffusion fMRI responses in rat visual cortex

This study examines how inhibiting aquaporin-4 channels affects BOLD and diffusion fMRI responses in rat visual cortex, showing increased BOLD amplitude but no change in diffusion responses.

Evaluation and Optimization of Motion Correction in Spinal Cord fMRI Preprocessing

This study evaluates motion correction methods for spinal cord fMRI, finding that 3D FLIRT with slice-wise regularization improves tSNR and reduces motion artifacts.

Arterial blood contrast (ABC) enabled by magnetization transfer (MT): a novel MRI technique for enhancing the measurement of brain activation changes

This paper introduces arterial blood contrast (ABC) as a novel MRI technique that enhances brain activation measurement by combining magnetization transfer with BOLD contrast, offering improved efficiency and spatial specificity.

High-Resolution Metabolic Mapping of the Cerebellum Using a Reduced Field of View (Zoomed) Magnetic Resonance Spectroscopic Imaging

This study develops a high-resolution MRSI technique for the cerebellum, enabling detailed metabolic mapping with improved spatial resolution and reduced artifacts.

A Multicenter Preclinical MRI Study: Definition of Rat Brain Relaxometry Reference Maps

This study demonstrates a multicenter preclinical MRI study using rat brains to create relaxometry reference maps by analyzing T1 and T2 maps across different imaging centers and processing pipelines.

Comparing fMRI responses measured at 3 versus 7 Tesla across human cortex, striatum, and brainstem

This study compares 7 T and 3 T fMRI responses in human brain regions during a decision-making task, finding greater 7 T benefits in subcortical areas like the brainstem.

Cerebral Metabolic Changes during Visuomotor Adaptation Assessed using Quantitative FMRI

This study uses calibrated fMRI to examine metabolic and blood flow changes during visuomotor adaptation in healthy humans, finding that CMRO2 decreases faster than BOLD or CBF but the flow-metabolism coupling ratio remains stable.

Methods for quantitative susceptibility and R2* mapping in whole post-mortem brains at 7T

The paper describes a pipeline for quantitative susceptibility and R2* mapping in post-mortem brains and compares results between ALS patients and controls using histology validation.

Most small cerebral cortical veins demonstrate significant flow pulsatility: a human phase contrast MRI study at 7T

The paper uses phase contrast MRI at 7T to show that most small cerebral cortical veins have significant flow pulsatility, introducing an automated method to detect this.

Multivoxel Pattern of Blood Oxygen Level Dependent Activity can be sensitive to stimulus specific fine scale responses

The paper evaluates the spatial precision of stimulus-specific BOLD responses using MVPA across cortical depths in V1, finding that multivoxel patterns can achieve sub-millimeter resolution.

Rapid event-related, BOLD, NHP: choose two out of three

The paper investigates rER BOLD fMRI in NHP, finding that while individual elements work well, their combination is challenging due to noise and motion artifacts.

Multi-parametric quantitative spinal cord MRI with unified signal readout and image denoising

This paper introduces a unified signal readout approach for multi-parametric spinal cord MRI, combined with MP-PCA denoising, improving the quality and consistency of microstructural metrics.

High-resolution MEMRI characterizes laminar specific ascending and descending spinal cord pathways in rats

This study uses MEMRI to visualize laminar-specific spinal cord pathways in rats, showing T1 signal enhancement in specific laminae after MnCl2 administration.

Weight Sensitivity of Temporal SNR Metrics in multi-echo fMRI

The paper analyzes weight sensitivity of temporal SNR metrics in multi-echo fMRI using a generalized Rayleigh quotient framework, showing high similarity in certain brain regions.

Removal of high frequency contamination from motion estimates in single-band fMRI saves data without biasing functional connectivity

This paper identifies and removes high-frequency motion artifacts in single-band fMRI data, improving motion estimates and reducing data loss without biasing functional connectivity.

Functional MRI of large scale activity in behaving mice

This paper develops an fMRI approach for whole-brain activity recording in behaving mice, demonstrating its use in complex tasks and reducing movement artefacts.

Proof of concept of a novel ex vivo, in situ method for MRI and histological brain assessment

This paper demonstrates that perfusion-based in situ fixation of ex vivo brains preserves structural integrity and antigenicity, enabling accurate MRI and histological analysis up to 10 months post-mortem.

Weight loss reduces head motion: re-visiting a major confound in neuroimaging

This study shows weight loss reduces head motion during MRI, suggesting potential biases in neuroimaging outcomes related to obesity.

A frequency-domain machine learning method for dual-calibrated fMRI mapping of oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen consumption (CMRO2)

This paper introduces a machine learning method for dual-calibrated fMRI to estimate OEF and CMRO2, showing reduced computation time, error, and bias compared to existing methods.

Temporal signal-to-noise changes in combined multiband- and slice-accelerated echo-planar imaging with a 20- and 64-channel coil

The paper evaluates how temporal signal-to-noise ratio (tSNR) changes with different acceleration techniques in EPI, showing that multiband acceleration has less impact on tSNR than slice acceleration.

Cerebrovascular reactivity assessment with O2-CO2 exchange ratio under brief breath hold challenge

The paper assesses cerebrovascular reactivity using the O2-CO2 exchange ratio during breath hold challenges and finds it better correlates with CBF changes than individual PCO2 or PO2 changes.

Inter-slice leakage and intra-slice aliasing in simultaneous multi-slice echo-planar images

This study investigates eye movement artefacts in simultaneous multi-slice fMRI data and shows that artefact severity depends on the phase-encoding direction.