Memory and Neural Mechanisms

This study uses optogenetics to disrupt theta rhythms in mice and shows that theta is essential for working memory retrieval but not for spatiotemporal coding.

This study identifies differential plasticity in striatal pathways that balance fear responses with and without sensory cues in mice.

The paper investigates neocortical activity during hippocampal ripples in awake mice, finding that deactivation and activation dominate post-ripple activity, with distinct subpopulations of neurons showing opposing firing rate changes.

The paper investigates how neuronal activity in the amygdala and hippocampus enhances emotional memory encoding and shows that inhibiting this activity reduces memory enhancement for emotional stimuli.

The paper shows that visual and hippocampal activity in humans reflects successor-like representations, predicting future events in visual sequences.

This paper presents a framework where a spiking neural network learns a cognitive map using spike-timing dependent plasticity, showing connections to TD(λ) algorithm and implications for behavior and experience replays.

The paper decodes human identity from neuronal activity using computer vision and deep learning, finding that tens of neurons in brain regions beyond MTL can robustly represent concepts.

This study tracks synaptic changes in the hippocampus during fear memory formation and extinction, showing synaptogenesis and synapse modification between CA3 and CA1 engram cells.

This study identifies cortical regions involved in representing confidence during probabilistic learning using a dynamic task and MRI.

The paper identifies long-range inhibitory input to layer 1 of the auditory cortex and shows its role in facilitating memory through plasticity during threat learning.

This study investigates how extrinsic inputs control early postnatal CA1 hippocampal circuits in mice, showing differential contributions from entorhinal and thalamic pathways to synchronous activity.

This study shows that voluntary alcohol consumption during early or late adolescence in rats affects adult fear behaviors differently in males and females.

The paper examines hippocampal-cortical co-reactivation during rest after encoding and links it to forgetting in humans.

This paper introduces a biologically plausible generative model of the hippocampal formation that uses theta-band oscillations to train a network for spatial and non-spatial memory tasks.

This study shows that LEC inputs drive dendritic spikes in CA1 pyramidal neurons via a disinhibitory VIP interneuron circuit, revealing a mechanism for context-specific hippocampal coding.

This study shows that Panx1 channels in both neurons and astrocytes are essential for long-term spatial reference memory in mice, as demonstrated by behavioral and electrophysiological experiments.

This study reveals distinct dorsoventral organization of hippocampal projections to the medial entorhinal cortex in rodents, showing different targeting patterns in dorsal and ventral regions.

This study shows that sleep deprivation does not cause memory loss but suboptimal storage, which can be retrieved using optogenetics or roflumilast.

The paper examines age-related differences in brain structural measures related to short- and long-delay memory consolidation in children and young adults, identifying distinct multivariate brain profiles associated with each memory type.

The paper shows that fan cells in the lateral entorhinal cortex (LEC) connect to the medial entorhinal cortex (MEC) layer 1, influencing MEC neurons through both excitation and inhibition.

The paper investigates the role of the orbitofrontal cortex in creating cognitive maps by showing that its inactivation disrupts specific cue-outcome associations but not model-based learning overall.

The paper investigates age-related changes in neuronal excitability in the hippocampus of mice, finding that aged mice show a deficit in ensemble-specific excitability after learning, linked to memory impairment.

This paper identifies a cortico-collicular circuit in mice that encodes shelter direction and is essential for accurate orientation during escape.

This study shows that reverberatory activity in the hippocampus links conditioned and unconditioned stimuli during memory encoding in mice.

The paper investigates the role of the MGN-BLA circuit in associative learning, finding that the MGN encodes arousal but not valence, while the BLA encodes both.

The paper shows place cells in the CA1 hippocampus cluster non-randomly by field location, using calcium imaging and statistical analysis in rats.

This study investigates rhythmic coordination between hippocampus and prefrontal cortex during odor-place associative memory tasks in rats, showing that beta and respiratory rhythms influence decision-making.

The paper analyzes human hippocampal recordings to evaluate hypotheses about theta oscillations' role in memory, finding that narrowband theta increases during successful encoding and retrieval, while broadband changes mask these effects.

This study shows emotional tagging enhances memory for neutral events through rapid neural reactivation and reorganization in the hippocampus and neocortex.

The paper identifies distinct circuit engagement by rostral and caudal BLA subregions in the prelimbic and infralimbic PFC through anatomical, electrophysiological, and optogenetic analyses.