Adipose Tissue and Metabolism

Loss of TLE3 Promotes Mitochondrial Program in Beige Adipocytes and Improves Glucose Metabolism

This study shows that loss of TLE3 enhances mitochondrial function in beige adipocytes, improves glucose metabolism, and prevents weight gain.

HDAC11 Suppresses the Thermogenic Program of Adipose Tissue via BRD2

This study shows that HDAC11 suppresses thermogenic programs in adipose tissue via BRD2, leading to improved metabolic outcomes in HDAC11-deficient mice.

CITGeneDB: A comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

CITGeneDB curates human and mouse genes that enhance or suppress cold-induced thermogenesis through perturbation experiments in mice, providing a searchable database for research on obesity and diabetes.

Estrogen receptor inhibition enhances cold-induced adipocyte beiging and glucose sensitivity

This study shows that estrogen receptor inhibition improves cold-induced adipocyte beiging and glucose sensitivity in mouse models.

Egr1 deficiency induces browning of inguinal subcutaneous white adipose tissue in mice

This study shows that Egr1 deficiency promotes browning of inguinal white adipose tissue in mice by enhancing Ucp1 expression and reducing extracellular matrix genes.

Cinnamon hydro alcoholic extract increased expression level of UCP3 gene in skeletal muscle of obese male Wistar Rats

This study shows cinnamon extract increases UCP3 gene expression in obese rats' skeletal muscle, with low doses being more effective than higher doses.