Neuroscience and Neural Engineering

This paper introduces two tangential insertion methods for high-density silicone probes in head-fixed mice to improve spatial sampling of hippocampal activity.

This study shows that multi-site optogenetic stimulation can increase firing rates in peripheral nerves through in silico, ex vivo, and in vivo experiments.

This paper designs an integrated circuit for intraocular visual prostheses that converts photoreceptor signals into RGC stimulation patterns without external processing.

This study evaluates electrode pooling in mouse sensorimotor cortex, finding that while some neuronal detail is lost, population dynamics for movement decoding are preserved.

The paper develops a comprehensive computational model of the human head to optimize visual brain-machine interfaces by simulating the entire visual pathway and surrounding tissues.

This paper extends Kilosort 2.0 to handle 3D neural probes by modifying spatial processing while keeping the core algorithm unchanged, improving resolution of spatial ambiguities.

This paper develops magnetic nanodiscs for wireless, cell-type specific activation of gut-brain circuits, showing they can regulate feeding behavior through hindbrain satiety circuits.

This study uses electrical stimulation to replicate natural spiking activity in primate retinal neurons, achieving lower variability than visual stimuli.

The paper develops a classifier to identify excitatory and inhibitory neurons using HD-MEA recordings without post-hoc labeling, revealing cell-type-specific network dynamics.

This paper introduces a microfluidic platform called directoids to study directional axonal growth between neural organoids, showing robust directional bias in axon outgrowth.

The paper demonstrates that a polymer-based retinal prosthesis can evoke physiologically relevant motion direction and speed responses in blind chick retinas.

This paper develops mechanically stable multi-electrode neural probes for high-resolution, multichannel recordings in peripheral nerves, improving signal yield and performance compared to single-electrode probes.

This paper introduces a live spike sorting system that achieves performance comparable to offline sorting and enables closed-loop interventions in neural recordings.

This paper introduces a biohybrid robot system using conductive fibers for low-power actuation, sensing, and closed-loop control, achieving autonomous locomotion and reduced muscle fatigue.

This paper introduces a water compartment cell culture lid that enables stable, long-term electrophysiological recordings of neuronal networks in vitro.

This paper introduces a minimally invasive EEG recording method in mice using thin needle electrodes, which reduces surgery time and improves animal welfare without compromising recording quality.

This paper introduces a compact wireless neural interface with on-device neuromorphic decoding for closed-loop optogenetics in rodents, achieving high accuracy with low computational resources.

This study uses a 3D neural probe to record electrical and chemical signals from surface and depth cortical neurons in response to auditory stimuli, revealing connectivity patterns and stimulus-selective spiking behavior.

This study identifies a conserved ECM regulatory axis linking traumatic brain injury, spinal cord injury, and neural implant-induced injury through transcriptomic analysis, highlighting HA-DAMP signaling as a potential biomarker for monitoring implant biocompatibility.

This paper introduces a printed self-folding cuff electrode with integrated rigid electrical components for chronic peripheral nerve interfacing, demonstrating reliable nerve recordings in locusts and rats.

This study uses single-cell spatial transcriptomics to analyze the brain's response to different microelectrode materials and sizes in rats, finding that electrode dimensions have a greater impact on tissue response than material type.

The paper describes bionic neurons that autonomously build integrated fluorescent fibrils and demonstrate neuromodulatory effects on neuronal function.

This study presents an ex vivo infrared nerve stimulation setup for rat sciatic nerves, demonstrating compound action potential evocation and identifying key artifacts in the method.

This paper introduces a low-cost, rapidly manufacturable flexible subdural electrode array for intraoperative cortical activity mapping, validated in vivo in rats.

OP-GLX enhances real-time processing and visualization of Neuropixels data by integrating with SpikeGLX for improved data handling during neural experiments.

This paper introduces REACH-Ctrl, a data-driven method for real-time control of cortical population activity using microstimulation and multi-electrode recordings, achieving high accuracy in macaque prefrontal cortex.

This paper introduces flex-ISMS, a flexible thin-film implant for intraspinal microstimulation, demonstrating depth selectivity and functional motor unit recruitment in pigs.

This paper introduces growth-adaptive spring electronics and a spike processing pipeline to enable long-term, same-neuron mapping in developing rat brains, revealing neuron-specific developmental decorrelation.

This study develops an in vitro model of demyelinated spinal cord tissue using human neural stem cells and chemical treatments to mimic demyelination and assess its physiological effects.