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The paper examines reproductive isolation in the Drosophila bipectinata species complex by analyzing hybrid sterility and mating behaviors, finding that pre-mating and post-mating barriers contribute to speciation.

This study identifies population-specific genetic strategies for agronomic traits in Coffea canephora using genomic analysis and machine learning, revealing distinct biological pathways in two populations.

This study shows that BAP1 deletion in hepatocytes leads to an inflammatory transcriptional response and impaired immune cell recruitment in the liver.

This paper introduces a spherical-harmonics regression method for PheWAS to detect localized genetic effects and summarize spatial complexity using rotation-invariant descriptors.

This study integrates multi-omics data to identify genes influencing yield in maize, showing improved resolution and predictive power compared to GWAS.

This study identifies TOCA-1 as a regulator of collateral branching in C. elegans neurons, showing it promotes actin assembly through WASP-1 and Arp2/3 complex activation.

The paper uses a multiparent yeast population to identify QTL for growth rates across environments, revealing context-dependent genetic architectures and allelic heterogeneity.

The paper tests a Y-linked Cas9 expression system in Drosophila melanogaster and finds reduced Cas9 activity, suggesting meiotic sex chromosome inactivation.

The paper reanalyzes mtDNA mutation data to determine if somatic mutations are under purifying selection, finding that apparent selection signals are due to germline mutations and most somatic mutations are neutral.

The paper investigates the role of the alternative complement pathway in Stargardt disease by analyzing Abca4-/- and Cfd-/- mice, finding that while the pathway drives complement activation, it does not reduce lipofuscin accumulation.

The paper directly identifies de novo mobile element insertions in human sperm using long-read sequencing and finds age-related increases in retrotransposition rates.

This paper describes a novel meiotic mutant in maize that produces unreduced female gametes, enabling clonal seed production when combined with another mutant, advancing synthetic apomixis research.

The paper introduces PCAN, a resource integrating high-throughput phenotyping of mouse models for Prader-Willi syndrome to evaluate phenotypes and therapeutic strategies.

This study shows that p97 and PML nuclear bodies regulate cGAS degradation after DNA damage, affecting the DNA damage response and senescence.

The paper shows that CLN3 can function independently of WHI5 in regulating cell size for Start in yeast, as the double mutant exhibits near-wild-type cell size.

This study examines how genotype and sex influence paraquat-induced oxidative stress effects on functional aging and lifespan in Drosophila melanogaster.

The paper identifies ZNF-236 as a key factor maintaining quiescence of stress-induced genes in C. elegans, showing that this silencing is an active genomic state, not passive.

The paper develops a machine-learning classifier to automate detection of ataxia and convulsions in Drosophila Shu mutants, showing reliable classification of walking and immobilization with moderate sensitivity for uncoordinated movement.

This study benchmarks five loss-of-function perturbation tools for studying noncoding genome function, finding dual-SpCas9 is most effective for targeting CREs and recommending RNA interference for noncoding RNA genes.