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The paper screens great ape museum specimens for DNA viruses, identifying multiple viruses and obtaining near-complete genomes, including high-coverage hepatitis B virus genomes.

The paper identifies DNA methylation and gene expression changes in human blood after a meal, linking them to cardiometabolic health and obesity-related genes.

This study shows cohesin and CTCF regulate gene expression through both architectural and direct transcriptional mechanisms, with CTCF also acting as a transcriptional activator independent of cohesin.

The paper presents a gap-free genome assembly of mung beans and identifies structural variations and selection pressures during domestication.

The paper investigates enhancer-promoter interactions and finds that gene-skipping enhancers are rare, with proximity and coactivator dependency better predicting functional relationships.

CGMFinder identifies correlated gene modules from 3H scRNA-seq data, outperforming existing methods in detecting biologically relevant modules.

The paper provides a unified VCF dataset from 1,498 maize accessions to explore genomic diversity using a standardized variant-calling pipeline.

The paper maps Z-DNA using ChIP-Seq with two Z-DNA biosensors, finding similar binding profiles but distinct gene associations.

The paper presents whole-genome DNA methylomes of tree shrew brains, revealing conserved and divergent DNA methylation patterns on sex chromosomes compared to other mammals.

This study identifies a novel Serratia sarumanii strain (GBS19) capable of degrading several pesticides, with genomic analysis confirming its degradation capacity and potential for bioremediation.

This study identifies context-specific regulatory effects of metabolic trait-associated variants in human skeletal muscle cells under different conditions.

This study identifies genetic variations in cytb, dhodh, and pin1 genes linked to buparvaquone resistance in Theileria annulata infecting dairy cattle in India using nanopore sequencing.

PanSci, a single-cell transcriptome atlas of over 20 million cells throughout the mouse lifespan, unveils the temporal architecture of aging-associated cellular population dynamics, organ-specific immune cell shifts, and the lymphocytes role in organismal aging.

CDR-Finder identifies hypomethylated regions in centromeres using long-read sequencing data and generates BED files and plots for analysis.

The paper identifies widespread isoform switches of transcription factors across human tissues and predicts their functional consequences.

The paper introduces the Nucleotide Transformer, a foundation model for genomics, showing it can predict molecular phenotypes from DNA sequences with transfer learning across tasks and organisms.

This study shows that changes in transposable element methylation during aging predict age and that demethylation of young L1s is linked to cancer.

This paper introduces a high-plex spatial molecular imaging technique capable of sub-cellular transcriptome analysis of FFPE tissues, achieving whole transcriptome coverage with high resolution and minimal dissociation bias.

The paper develops a decontamination pipeline to detect and remove contamination in genomic data, revealing rare introgression in Lasius ants.

The paper reports the assembly of multiple IGH haplotypes from Mauritian cynomolgus macaques using long-read sequencing, revealing genetic diversity and novel alleles not previously cataloged.