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The paper develops a reduced-order model for plasma transport in tumors by integrating CFD simulations with a RAD model, showing improved accuracy with EHD effects.

The paper shows immune cells regulate circulating adipocyte extracellular vesicle levels by clearing EVs, with reduced clearance in obesity leading to increased circulating adipoEVs.

The paper investigates NRAC's role in reciprocal adipose-heart regulation of fatty acid metabolism across nutritional states using human and mouse data.

This study investigates tissue-specific regulation of PNPLA3 in mice, showing feeding increases hepatic PNPLA3 while cold exposure boosts it in brown adipose tissue through post-transcriptional mechanisms, linking it to lipid remodeling in response to metabolic stress.

Oral Faecalibacterium prausnitzii, the taxon most consistently depleted in PD stool, improved motor and GI deficits and lowered α-synuclein aggregates in male Thy1-ASO mice.

This study shows that mice exhibit persistent hyperphagia after a weight-loss intervention, with weight regain linked to initial weight gain on a high-fat diet.

This study compares menthol and thermal stress as methods to induce bleaching in staghorn coral, finding menthol more effective at reducing algal symbiont photosynthetic capacity without harming coral health.

This study investigates how SLC4A1 mutations in dRTA affect intracellular pH and autophagy in mouse kidney cells.

This study shows that transferring gut microbiota from young and estropausal mice improves ovarian function and fertility in adult mice.

This study characterizes the biomechanical properties of porcine lower limb arteries to evaluate their suitability as preclinical models for peripheral vascular devices.

This study shows that morning endurance training in mice leads to better performance adaptations than afternoon training, despite lower training volumes.

This study identifies Dgat2 as a key modulator linking amyloid pathology, lipid dysregulation, and neuroinflammation in Alzheimer's disease across Drosophila and mouse models.

This study shows that genetic deletion of ASIC3 reduces left ventricular dilation and improves autonomic function after myocardial infarction in mice.

This study shows that microtubule detyrosination in HCM causes nuclear shape changes and YAP1 signaling, which can be reversed by inhibiting detyrosination.

The paper compares physiological responses to aversive and nonaversive audiovisual, auditory, and imagined auditory stimuli, finding consistent EMGc differentiation across modalities.

The paper identifies a novel mechanoadaptive process in intervertebral discs through collagenesis, revealing TRPV4's role in collagen II synthesis and mechanical stress adaptation.

This study uses gas exchange measurements to assess growth, energy use, and body composition of black soldier fly larvae on diets with different protein-to-carbohydrate ratios.

This study shows repeated disuse atrophy creates a molecular memory in skeletal muscle, leading to transcriptional resilience in young adults but increased susceptibility in aged muscle.

This study shows that loss of mtASIC1a in PASMCs under chronic hypoxia leads to mitochondrial dysfunction and apoptosis resistance.

This study examines metabolic changes in brown adipose tissue during cold deacclimation, identifying rapid adaptations in N-acetylated amino acid metabolism.