Author

A. A. Kennedy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. W. Tai· 3 shared A. E. Hargrove· 1 shared A. G. Monaghan· 1 shared A. S. Lauring· 1 shared B. S. Tolbert· 1 shared B. T. Emmer· 1 shared C. E. Wobus· 1 shared C. Haddad· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

A. W. Tai

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Type I interferon signaling induces a delayed antiproliferative response in Calu-3 cells during SARS-CoV-2 infection

J. B. Cunha, K. Leix, E. J. Sherman, C. Mirabelli, A. A. Kennedy, A. S. Lauring, A. W. Tai, C. E. Wobus, B. T. Emmer

This study identifies type I interferon signaling as inducing a delayed antiproliferative response in Calu-3 cells during SARS-CoV-2 infection, which may impair alveolar regeneration.

bioRxiv · Feb 28, 2023 · PreprintMicrobiology

A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine

S. Jangra, J. J. Landers, R. Rathnasinghe, J. J. O'Konek, K. W. Janczak, M. Cascalho, A. A. Kennedy, A. W. Tai, J. R. Baker, M. Schotsaert, P. T. Wong

This study develops a combination adjuvant that enhances antiviral immune responses to a SARS-CoV-2 protein vaccine, showing improved TH1 responses and neutralizing antibodies against variants in mice.

bioRxiv · Feb 18, 2021Immunology

Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures

M. Zafferani, C. Haddad, L. Luo, J. Davila-Calderon, L. Yuan-Chiu, C. Shema Mugisha, A. G. Monaghan, A. A. Kennedy, J. D. Yesselman, R. R. Gifford, A. W. Tai, S. B. Kutluay, M.-L. Li, G. Brewer, B. S. Tolbert, A. E. Hargrove

This study identifies amilorides as small molecules that inhibit SARS-CoV-2 replication by targeting conserved RNA structures in the 5-UTR region.

bioRxiv · Dec 5, 2020Microbiology