Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
J. G. Hoffstadt, J. W. Wotring, S. Porter, B. S. Halligan, M. J. O'Meara, A. W. Tai, J. Z. Sexton
This study identifies four nanomolar inhibitors of Dengue Virus replication using high-content screening and a viral pseudotime model.
bioRxiv · Mar 24, 2023 · PreprintCell Biology
J. B. Cunha, K. Leix, E. J. Sherman, C. Mirabelli, A. A. Kennedy, A. S. Lauring, A. W. Tai, C. E. Wobus, B. T. Emmer
This study identifies type I interferon signaling as inducing a delayed antiproliferative response in Calu-3 cells during SARS-CoV-2 infection, which may impair alveolar regeneration.
bioRxiv · Feb 28, 2023 · PreprintMicrobiology
J. Zhang, A. Kennedy, D. M. de Melo Jorge, L. Xing, W. Reid, S. Bui, J. Joppich, M. Rose, S. Ercan, Q. Tang, A. W. Tai, Y. Wang
This study shows SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion by altering its structure and function.
bioRxiv · Mar 4, 2022Cell Biology
S. Jangra, J. J. Landers, R. Rathnasinghe, J. J. O'Konek, K. W. Janczak, M. Cascalho, A. A. Kennedy, A. W. Tai, J. R. Baker, M. Schotsaert, P. T. Wong
This study develops a combination adjuvant that enhances antiviral immune responses to a SARS-CoV-2 protein vaccine, showing improved TH1 responses and neutralizing antibodies against variants in mice.
bioRxiv · Feb 18, 2021Immunology
M. Zafferani, C. Haddad, L. Luo, J. Davila-Calderon, L. Yuan-Chiu, C. Shema Mugisha, A. G. Monaghan, A. A. Kennedy, J. D. Yesselman, R. R. Gifford, A. W. Tai, S. B. Kutluay, M.-L. Li, G. Brewer, B. S. Tolbert, A. E. Hargrove
This study identifies amilorides as small molecules that inhibit SARS-CoV-2 replication by targeting conserved RNA structures in the 5-UTR region.
bioRxiv · Dec 5, 2020Microbiology
D. L. Lin, N. A. Cherepanova, L. Bozzacco, M. R. MacDonald, R. Gilmore, A. W. Tai
This study identifies the STT3B-containing oligosaccharyltransferase complex as essential for dengue virus infection, revealing its oxidoreductase activity is required for viral propagation.
bioRxiv · Jun 1, 2017Microbiology