Author

Dong Shin Park

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Li‐Huei TsaiiD· 2 shared M KellisiD· 2 shared Abigail K. R. Lytton‐JeaniD· 1 shared Adele Bubnys· 1 shared Alan Y. L. JiangiD· 1 shared Alice E. StantoniD· 1 shared Anjanet R. Loon· 1 shared Benjamin T. JamesiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

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10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Li‐Huei TsaiORCID

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3 papers

Recent·Most cited

Engineered 3D Immuno-Glial-Neurovascular Human miBrain Model

Alice E. Stanton, Adele Bubnys, Emre Agbas, Benjamin T. James, Dong Shin Park, Alan Y. L. Jiang, Rebecca L. Pinals, Liwang Liu, Nhat Truong, Anjanet R. Loon, Colin Staab, Oyku Cerit, Hsin-Lan Wen, David V. Mankus, Margaret E. Bisher, , Li‐Huei Tsai

The paper constructs a 3D human brain model integrating multiple cell types to study Alzheimer's Disease mechanisms linked to APOE4.

Proceedings of the National Academy of Sciences · Oct 17, 2025Peer-reviewedNeuroscience

Multisensory gamma stimulation enhances adult neurogenesis and improvescognitive function in male mice with Down Syndrome

Rezaul Islam, Brennan Jackson, Maeesha Tasnim Naomi, Brooke Schatz, Noah Tan, Mitchell H. Murdock, Dong Shin Park, Daniela Rodrígues-Amorím, Xueqiao Jiang, Sergio Sebastian Pineda, Chinnakkaruppan Adaikkan, Vanesa S. Fernandez Avalos, Ute Geigenmüller, Rosalind Mott Firenze, M Kellis, , Li‐Huei Tsai

This study shows that multisensory gamma stimulation improves cognitive function and adult neurogenesis in Ts65Dn mice, a model of Down syndrome.

PLoS ONE · Apr 24, 2025Peer-reviewedNeuroscience

Expanded huntingtin CAG repeats disrupt the balance between neural progenitor expansion and differentiation in human cerebral organoids

Jinqiu Zhang, Jolene Ooi, Kagistia Hana Utami, Sarah R. Langley, Obed Akwasi Aning, Dong Shin Park, Magdalena Renner, Shiming Ma, Chit Fang Cheok, Juergen A. Knoblich, Florent Ginhoux, Enrico G. Petretto, Mahmoud A. Pouladi

This study shows that expanded CAG repeats in HTT disrupt neural progenitor expansion and differentiation in human cerebral organoids, suggesting abnormal neurodevelopment in Huntington disease.

bioRxiv · Nov 26, 2019 · PreprintDevelopmental Biology