Lipid-anchored Proteasomes Control Membrane Protein Homeostasis
R. Zhang, S. Pan, S. Zheng, Q. Liao, Z. Jiang, D. Wang, X. Li, A. Hu, X. Li, Y. Zhu, X. Shen, X. Zhang, L. Huang, J. Lei, S. Zhong, , X. Guo
This study identifies N-myristoylation of Rpt2 as a mechanism for proteasome-membrane interaction, showing its role in membrane protein homeostasis and its impact on cellular processes and tumor growth.
bioRxiv · May 12, 2023Biochemistry