Author

Brett G. Larsen

Lunenfeld-Tanenbaum Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:protein design· 2 Research Focus:protein structure prediction· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Anne‐Claude GingrasiD· 2 shared Cassandra J. WongiD· 2 shared Alissa J. NelsoniD· 1 shared Anthony P. PossematoiD· 1 shared Audrey AstoriiD· 1 shared Barry M. ZeeiD· 1 shared Bin ZhangiD· 1 shared Brian RaughtiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersSystems Biology

Anne‐Claude GingrasORCID

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Author profile →

3 papers

Recent·Most cited

Expanding the Global Map of Protein Post Translational Modifications with Immunoaffinity Enrichment and nDIA Analysis on the Orbitrap Astral Mass Spectrometer

Mukesh Kumar, Anthony P. Possemato, Barry M. Zee, Srikanth Subramanian, Jian Min Ren, Alissa J. Nelson, Bin Zhang, Sean D. Landry, Jeffrey C. Silva, Brett G. Larsen, Tonya Pekar Hart, Matthew P. Stokes, Sean A. Beausoleil

This study identifies numerous post-translational modification sites using immunoaffinity enrichment and nDIA mass spectrometry, showing nDIA's superior coverage and efficiency.

Molecular & Cellular Proteomics · Apr 6, 2026Peer-reviewedBiochemistry

Mapping Protein-Protein Interactions Using Data-Dependent Acquisition Without Dynamic Exclusion

Shen Zhang, Brett G. Larsen, Karen Colwill, Cassandra J. Wong, Ji‐Young Youn, Anne‐Claude Gingras

The paper compares noDE and DDA/DIA methods for protein-protein interaction detection, finding noDE provides better sensitivity and identifies more high confident interactors.

Analytical Chemistry · Jul 18, 2022Peer-reviewedSystems Biology

A SARS-CoV-2 - host proximity interactome

Payman Samavarchi‐Tehrani, Hala S. Abdouni, James D.R. Knight, Audrey Astori, Reuben Samson, Zhen‐Yuan Lin, Dae‐Kyum Kim, Jennifer J. Knapp, Jonathan R. St‐Germain, Christopher D. Go, Brett G. Larsen, Cassandra J. Wong, Patricia Cassonnet, Caroline Demeret, Yves Jacob, , Anne‐Claude Gingras

Proximity-dependent biotinylation of 27 SARS-CoV-2 proteins in A549 cells maps 7810 virus-host proximity interactions across 2242 host proteins, including membrane-associated partners missed by affinity purification.

bioRxiv · Sep 3, 2020 · PreprintSystems Biology