C. T. Chaton

Glycosylation of serine/threonine-rich intrinsically disordered regions of membrane-associated proteins in streptococci

The paper identifies glycosylation of serine/threonine-rich IDRs in streptococcal membrane proteins and shows its role in biofilm formation.

Mechanistic basis of staphylococcal interspecies competition for skin colonization

This study investigates the structural and functional basis of staphylococcal adhesion to skin and reveals cross-inhibition between S. epidermidis and S. aureus.

Modification of cell wall polysaccharide spatially controls cell division in Streptococcus mutans

This study shows that GroP-deficient immature SCCs spatially coordinate AtlA and MapZ localization in S. mutans, ensuring proper cell division and morphology.

PE5-PPE4-EspG3 trimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems

The paper presents the crystal structure of a PE5-PPE4-EspG3 trimer from the ESX-3 system, revealing unique interactions and structural dynamics compared to the ESX-5 system.

Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site

The paper determines the crystal structures of three homoserine transacetylases and identifies MtMetX as highly druggable.

Structural variability of EspG chaperones from mycobacterial ESX-1, ESX-3 and ESX-5 type VII secretion systems

The paper reports crystal and SAXS structures of EspG chaperones from mycobacterial ESX systems, revealing structural variability and potential substrate binding modes.