Author

C. Tiede

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

D. C. Tomlinson· 3 shared A. Cleasby· 1 shared A. Curd· 1 shared A. Flynn· 1 shared A. J. Fielding· 1 shared A. J. Wilson· 1 shared A. N. Calabrese· 1 shared B. I. Wicky· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersBiochemistry

D. C. Tomlinson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural characterization and inhibition of the interaction between ch-TOG and TACC3

J. Shelford, S. G. Burgess, E. Rostkova, M. W. Richards, C. Tiede, A. J. Fielding, T. Daviter, D. C. Tomlinson, A. N. Calabrese, M. Pfuhl, R. Bayliss, S. J. Royle

This study determines the structure of the ch-TOG-TACC3 interaction and shows that inhibiting it causes pericentriolar material fragmentation and delayed mitosis.

bioRxiv · May 31, 2024Cell Biology

Exploiting the Affimer platform against influenza A virus

O. Debski-Antoniak, A. Flynn, D. P. Klebl, C. Tiede, I. A. Wilson, S. P. Muench, D. Tomlinson, J. Fontana

This paper isolates and characterizes Affimers, antibody-like proteins, that inhibit influenza A virus H3 subtype infection in vitro and block HA-receptor interactions.

bioRxiv · Aug 22, 2023Microbiology

Piggybacking on the Cholera Toxin: Identification of a Toxoid-binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons

M. R. Balmforth, J. Haigh, C. Tiede, D. C. Tomlinson, J. Deuchars, M. E. Webb, W. B. Turnbull

The paper identifies two antibody mimetics that bind to cholera toxin B-subunit and demonstrate selective delivery to motor neurons in vivo.

bioRxiv · May 11, 2020Biochemistry

Nanoscale pattern extraction from relative positions of sparse 3D localisations

A. Curd, J. Leng, R. Hughes, A. Cleasby, B. Rogers, C. Trinh, M. Baird, Y. Takagi, C. Tiede, C. Sieben, S. Manley, T. Schlichthaerle, R. Jungmann, J. Ries, H. Shroff, M. Peckham

The paper introduces a method to extract high-resolution ordered features from localisation microscopy data by analyzing relative molecular positions, applied to infer ultrastructure of various biological structures.

bioRxiv · Feb 13, 2020Cell Biology

Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs

T. A. Edwards, J. A. Miles, F. Hobor, J. L. Taylor, C. Tiede, P. L. Rowell, C. H. Trinh, B. R. Jackson, F. A. Nadat, H. F. Kyle, B. I. Wicky, J. Clarke, D. C. Tomlinson, A. J. Wilson

The paper identifies Affimer reagents that selectively bind BCL-2 family proteins through non-canonical structural motifs, showing competitive inhibition and conformational changes.

bioRxiv · May 27, 2019 · PreprintBiochemistry