Author

D. C. Tomlinson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. Tiede· 2 shared A. J. Wilson· 1 shared A. P. Droop· 1 shared A. Roe· 1 shared A. Zeltina· 1 shared B. da Silva· 1 shared B. I. Wicky· 1 shared B. R. Jackson· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiochemistry

C. Tiede

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

VelcroVax: a bolt-on vaccine platform technology improves antibody titres against a viral glycoprotein in mice

N. J. Stonehouse, N. J. Kingston, K. Grehan, J. S. Snowden, M. Hassall, J. Alzahrani, G. C. Paesen, L. Sherry, C. R. Hayward, A. Roe, S. Stephen, D. C. Tomlinson, A. Zeltina, K. J. Doores, N. A. Ranson, , D. J. Rowlands

VelcroVax is a vaccine platform that enhances antibody titres against a viral glycoprotein in mice by combining a modified VLP with a SUMO-tagged antigen.

bioRxiv · Apr 22, 2022 · PreprintImmunology

Piggybacking on the Cholera Toxin: Identification of a Toxoid-binding Protein as an Approach for Targeted Delivery of Proteins to Motor Neurons

M. R. Balmforth, J. Haigh, C. Tiede, D. C. Tomlinson, J. Deuchars, M. E. Webb, W. B. Turnbull

The paper identifies two antibody mimetics that bind to cholera toxin B-subunit and demonstrate selective delivery to motor neurons in vivo.

bioRxiv · May 11, 2020Biochemistry

A high-content screen profiles cytotoxic microRNAs in pediatric and adult glioblastoma cells and identifies miR-1300 as a potent inducer of cytokinesis failure

M. Boissinot, H. King, M. Adams, J. Higgins, T. A. Ward, L. P. Steele, D. Tams, R. Morton, E. Polson, B. da Silva, A. P. Droop, J. L. Hayes, H. Martin, P. Laslo, E. E. Morrison, , S. C. Short

This study identifies miR-1300 as a potent cytotoxic microRNA in glioblastoma cells, causing cytokinesis failure and apoptosis, with potential therapeutic applications.

bioRxiv · Oct 1, 2019 · PreprintCancer Biology

Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs

T. A. Edwards, J. A. Miles, F. Hobor, J. L. Taylor, C. Tiede, P. L. Rowell, C. H. Trinh, B. R. Jackson, F. A. Nadat, H. F. Kyle, B. I. Wicky, J. Clarke, D. C. Tomlinson, A. J. Wilson

The paper identifies Affimer reagents that selectively bind BCL-2 family proteins through non-canonical structural motifs, showing competitive inhibition and conformational changes.

bioRxiv · May 27, 2019 · PreprintBiochemistry