Author

Carla Mulas

King's College LondonORCID 0000-0002-9492-6482Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Austin G SmithiD· 3 shared Jennifer NicholsiD· 2 shared Kevin J. ChalutiD· 2 shared Tüzer Kalkan· 2 shared Alexander K. WinkeliD· 1 shared Anna L. EllermanniD· 1 shared Ayaka YanagidaiD· 1 shared Connor Ross· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersDevelopmental Biology

Austin G SmithORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ERK signalling orchestrates metachronous transition from naive to formative pluripotency

Carla Mulas, Melanie Stammers, Siiri I. Salomaa, Constanze Heinzen, David M. Suter, Austin G Smith, Kevin J. Chalut

This study shows ERK signalling dismantles the naive pluripotent state and preserves pluripotency during transition to formative pluripotency in mouse embryonic stem cells.

bioRxiv · Jul 20, 2023 · PreprintDevelopmental Biology

Plakoglobin is a mechanoresponsive regulator of naïve pluripotency

Timo N. Kohler, Joachim De Jonghe, Anna L. Ellermann, Ayaka Yanagida, Michael Herger, Erin M. Slatery, Katrin Fischer, Carla Mulas, Alexander K. Winkel, Connor Ross, Sophie Bergmann, Kristian Franze, Kevin J. Chalut, Jennifer Nichols, Thorsten Boroviak, Florian Hollfelder

This study shows that Plakoglobin regulates naive pluripotency in mouse ESCs through mechanosensitivity, with expression specific to the blastocyst stage in human and mouse embryos.

bioRxiv · Mar 13, 2022 · PreprintDevelopmental Biology

Nodal secures pluripotency upon embryonic stem cell progression from the ground state

Carla Mulas, Tüzer Kalkan, Austin G Smith

This study shows that Nodal maintains pluripotency in mouse ES cells as they exit the ground state, enabling competence for germline and somatic lineage specification.

Stem Cell Reports · Jun 29, 2017Peer-reviewedDevelopmental Biology

Tracking the embryonic stem cell transition from ground state pluripotency

Tüzer Kalkan, Nelly N. Olova, Mila Roode, Carla Mulas, Heather J Lee, Isabelle R. E. Nett, Hendrik Marks, Rachael V. Walker, Hendrik G. Stunnenberg, Kathryn Susan Lilley, Jennifer Nichols, Wolf Reik, Paul Bertone, Austin G Smith

The paper tracks the transition of mouse embryonic stem cells from ground state pluripotency to a formative phase, showing acute exit from naive status and transcriptome changes similar to early post-implantation epiblast.

Development · Feb 7, 2017Peer-reviewedDevelopmental Biology