Author

D. Mugahid

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Organism:non-human primate· 2 Research Focus:cell signaling & trafficking· 1 Assay:clinical cohort / trial· 1 Organism:Drosophila· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. L. Flynn· 3 shared P. L. Lin· 3 shared S. M. Fortune· 3 shared M. Chao· 2 shared M. Rodgers· 2 shared P. Maiello· 2 shared A. K. Shalek· 1 shared B. J. Braunecker· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

J. L. Flynn

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CD4+ T cells are homeostatic regulators during Mtb reinfection

J. Bromley, S. K. C. Ganchua, S. K. Nyquist, P. Maiello, M. Chao, H. J. Borish, M. Rodgers, J. Tomko, K. Kracinovsky, D. Mugahid, S. N. Nguyen, D. Wang, J. M. Rosenberg, E. C. Klein, H. P. Gideon, , J. L. Flynn

The paper shows that CD4+ T cells reduce inflammation and disease severity during Mtb reinfection by reprogramming CD8+ T cells and innate immune cells.

bioRxiv · Dec 20, 2023 · PreprintImmunology

Antibiotic treatment does not abrogate protection against Mycobacterium tuberculosis reinfection

S. K. Ganchua, P. Maiello, M. Chao, F. Hopkins, D. Mugahid, P. L. Lin, S. M. Fortune, J. L. Flynn

This study shows antibiotic treatment after primary Mtb infection reduces lung inflammation but does not eliminate protection against reinfection in macaques.

bioRxiv · Dec 19, 2023Microbiology

Development of an Engineered Mycobacterium tuberculosis Strain for a Safe and Effective Tuberculosis Human Challenge Model

X. Wang, H. Su, J. B. Wallach, J. C. Wagner, B. J. Braunecker, M. Gardner, K. M. Guinn, T. Klevorn, K. Lin, Y. J. Liu, Y. Liu, D. Mugahid, M. Rodgers, J. Sixsmith, S. Wakabayashi, , D. Schnappinger

This paper develops an engineered Mycobacterium tuberculosis strain with kill switches for a safe TB human challenge model, showing rapid clearance and low escape rates.

bioRxiv · Nov 19, 2023 · PreprintMicrobiology

YAP independently regulates cell size and population growth dynamics via non-cell autonomous mediators

D. Mugahid, M. Kalocsay, S. Gruver, L. Peshkin, M. W. Kirschner

This study shows YAP regulates cell size and population growth through separate non-cell autonomous mechanisms, with CYR61 mediating growth but not size.

bioRxiv · Nov 29, 2018Cell Biology