D. P. Beiting

NF-κB Signaling is Required for X-Chromosome Inactivation Maintenance Following T cell Activation

This study shows that NF-κB signaling is necessary for maintaining X-chromosome inactivation in female T cells after activation.

Genetic ablation of a female specific Apetala 2 transcription factor blocks oocyst shedding in Cryptosporidium parvum

This study identifies AP2-F as essential for oocyst shedding and transmission in Cryptosporidium parvum using a conditional gene ablation system.

Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8+ T cell response during acute and chronic toxoplasmosis

This paper investigates how secondary TCR engagement affects CD8+ T cell heterogeneity during acute and chronic toxoplasmosis, showing its role in effector responses but limited impact on memory populations.

Inflammatory monocytes promote pyogranuloma formation to counteract Yersinia blockade of host defense

This study shows that Yersinia pseudotuberculosis induces pyogranulomas in the murine intestine by blocking phagocytosis, and that monocytes are essential for granuloma formation and immune control.

A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition

This paper identifies a type III interferon response to Cryptosporidium requiring TLR3-dependent recognition, which protects against infection in mice.

Gut microbiota features associated with Clostridioides difficile colonization in dairy calves

This study identifies microbial features associated with C. difficile colonization in dairy calves using 16S rRNA sequencing, finding increased levels of specific taxa and reduced microbial co-occurrences in colonized calves.

Genetic targeting of Card19 is linked to disrupted Ninj1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection

This study shows that genetic targeting of Card19 disrupts Ninj1 expression, impairs macrophage cell lysis, and increases susceptibility to Yersinia infection.

Crosstalk between enterocytes and innate lymphoid cells drives early IFN-g-mediated control of Cryptosporidium

This study shows enterocytes promote ILC production of IFN-gamma, which restricts Cryptosporidium growth by acting on enterocytes themselves.

Remodeling of the maternal gut microbiome during pregnancy is shaped by parity

This study shows that maternal parity influences gut microbiome changes during pregnancy and affects offspring microbiota composition in pigs.

Natural infection with Giardia is associated with altered community structure of the human and canine gut microbiome.

This study investigates the impact of Giardia infection on gut microbiome structure in dogs and children, finding significant microbiome remodeling associated with infection.

MicrobiomeDB: a systems biology platform for integrating, mining and analyzing microbiome experiments.

MicrobiomeDB is a platform that integrates and analyzes microbiome data, enabling users to explore microbial community diversity and identify taxa linked to experimental variables.