Author

E. Rydkina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Seluanov· 2 shared V. Gorbunova· 2 shared X. Tian· 2 shared Z. Zhang· 2 shared A. Cornwell· 1 shared A. Tyshkovskiy· 1 shared B. Roy· 1 shared D. Firsanov· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPhysiology

A. Seluanov

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Author profile →

2 papers

Recent·Most cited

Increased hyaluronan by naked mole-rat HAS2 extends lifespan in mice

Z. Zhang, X. Tian, J. Y. Lu, K. Boit, J. Ablaeva, F. T. Zakusilo, S. Emmrich, D. Firsanov, E. Rydkina, S. A. Biashad, Q. Lu, A. Tyshkovskiy, V. N. Gladyshev, S. Horvath, A. Seluanov, V. Gorbunova

This study shows that overexpressing the naked mole-rat HAS2 gene in mice increases hyaluronan levels, reduces inflammation, and extends lifespan and healthspan.

bioRxiv · May 4, 2023 · PreprintPhysiology

Dampened PI3K/AKT signaling contributes to cancer resistance of the naked mole rat

J. Zhao, X. Tian, Y. Zhu, Z. Zhang, E. Rydkina, Y. Yuan, H. Zhang, B. Roy, A. Cornwell, E. Nevo, X. Shang, R. Huang, K. Kristiansen, A. Seluanov, X. Fang, V. Gorbunova

This study compares transcriptional responses to oncogenes in cancer-resistant and -prone species, finding that naked mole rat cells resist Ras-induced changes due to dampened PI3K/AKT signaling.

bioRxiv · Feb 27, 2020 · PreprintCancer Biology