F. D'Alessio

Immunogenicity of COVID-eVax Is Moderately Impacted by Temperature and Molecular Isoforms

This study shows that the immunogenicity of the plasmid DNA vaccine COVID-eVax is not significantly affected by temperature or DNA isoform changes.

Pseudomonas aeruginosa Elicits Sustained IL-1β Upregulation in Alveolar Macrophages from Lung Transplant Recipients

This study shows that Pseudomonas aeruginosa and its dominant microbiota increase IL-1β production in alveolar macrophages from lung transplant recipients, which can be reduced by inflammasome inhibitors.

MK2 Expression Promotes Non-Small Cell Lung Cancer Cell Death and Predicts Survival

This study shows MK2 promotes apoptosis in non-small cell lung cancer by facilitating caspase 3 nuclear translocation, and higher MK2 expression correlates with better patient survival.

Bet-hedging antimicrobial strategies in macrophage phagosome acidification drive the dynamics of Cryptococcus neoformans intracellular escape mechanisms

This study identifies that stochastic phagosomal acidification and oxidative stress drive stochastic Dragotcytosis in Cryptococcus neoformans, enabling fungal escape from macrophages.

Sex differences in lung imaging and SARS-CoV-2 antibody responses in a COVID-19 golden Syrian hamster model

This study shows that male golden Syrian hamsters experience more severe lung disease and lower antiviral antibody responses compared to females after SARS-CoV-2 infection.