F. Gao

This study identifies three ultrapotent SARS-CoV-2 neutralizing antibodies effective against B.1.351 variants, showing synergistic effects and protective efficacy in mice.

This study shows SUMOylation of GMFB increases its stability and trans-localization, upregulating inflammatory pathways in RPE cells under oxidative stress and inflammation.

This study identifies age and ethnicity-specific gene expression biomarkers for immune aging using transcriptomic data from peripheral blood mononuclear cells.

This paper demonstrates the first use of high-energy X-rays in FLASH radiotherapy, showing effective tumor control and tissue protection in mice.

The paper identifies cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 epitope and its variants, showing their ability to activate and kill infected cells.

This study compares the therapeutic effects of Remdesivir and Au22Glutathione18 in COVID-19 golden hamsters, finding that the gold compound better suppresses viral replication and inflammation.

The paper develops a minimally invasive epidural probe using diffuse correlation spectroscopy to monitor spinal cord blood flow and demonstrates its ability to detect ischemia in a porcine model.

This study shows that necrotizing enterocolitis (NEC) in preterm pigs leads to systemic immune suppression, increasing susceptibility to secondary infections.

This study identifies a linear epitope on SARS-CoV-2 S-RBD recognized by a potent neutralizing antibody and shows its potential for vaccine design.

This study analyzes HIV-1 env gene evolution in 12 perinatal transmission pairs, finding that most infections occur within two months of birth and fetal viruses show unique selection pressures.

This paper introduces a rapid screening system to identify potent neutralizing antibodies against SARS-CoV-2 and demonstrates its effectiveness in discovering high-potency antibodies.

This study isolates multiple SARS-CoV-2-neutralizing antibodies through site-directed screening, showing potent protection against virus infection.

This study shows that miR-203 suppresses pancreatic cancer cell proliferation, invasion, and migration by down-regulating FGF2 expression.

The paper identifies recombination and purifying selection in coronaviruses from different hosts as key factors in SARS-CoV-2 emergence.

This study evaluates whether maternal HIV Env vaccination boosts autologous virus neutralization in HIV-infected pregnant women, finding no significant enhancement in neutralization potency.

The paper shows that IRE1α activation enhances neutrophil antimicrobial functions like IL-1β production, NET formation, and MRSA killing.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

This study tracks the development of a potent ZIKV-specific antibody in a convalescent human, revealing limited somatic hypermutation and high germline identity.

The paper uses M13 phage display to identify a neutral, hydrophilic peptide that enhances permeation through hyperconcentrated mucin.

This study uses single-cell RNA-seq to analyze human infant retina, identifying cell types, communication networks, and developmental changes, providing a resource for retinal research and regenerative medicine.

This study uses single-cell RNA sequencing to analyze the cellular diversity and molecular markers in the retina of a trisomy 21 fetus, revealing communication networks and novel markers.

This study shows that inhibiting TG2 increases radiosensitivity in NSCLC by disrupting TOPOIIα-mediated DNA repair.

The paper investigates the Prp8 intein in Cryptococcus neoformans, showing that copper and zinc inhibit intein splicing through distinct mechanisms, potentially affecting spliceosome function.

The paper characterizes expression quantitative trait loci (eQTL) in bipolar disorder pedigrees to understand genetic regulation and heritability.