K. Cao

Development of an Accelerated Cellular Model for Alzheimer's Disease

This study uses progerin to accelerate AD phenotypes in neural progenitor cells with FAD mutations, showing increased tau phosphorylation, amyloid plaques, and cell death within weeks.

Disulfiram Exerts anti-pulmonary Fibrosis Effect by Activating PGE2 Synthesis

This study shows that Disulfiram reduces pulmonary fibrosis by reactivating COX-2-mediated PGE2 synthesis in both cell and animal models.

Coupled Biomechanical and Ionic Excitability in Developing Neural Cell Networks

The paper measures biomechanical dynamics of actin polymerization in neural precursor cells and shows its impact on ionic dynamics and cell-cell coupling during differentiation.

The Geometric Evolution of Aortic Dissections: Predicting Surgical Success using Fluctuations in Integrated Gaussian Curvature

This paper introduces a geometric descriptor based on integrated Gaussian curvature to predict surgical success in aortic dissections by analyzing shape changes.

Lysine acetylation regulates antibiotic resistance in Escherichia coli

This study identifies acetylation as a regulatory mechanism in antibiotic resistance in E. coli, showing it negatively affects metabolism but positively influences motility, with PykF acetylation playing a key role.

Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage

This study shows mitochondrial dysfunction promotes DNA damage through caspase-dependent mechanisms regulated by mitochondrial dynamics.

Undersampling correction methods to control γ-dependence for comparing β-diversity between regions

This study evaluates undersampling correction methods for β-diversity to reduce γ-dependence, finding that diversity accumulation curves outperform null models in removing γ-dependence.

Species packing and the latitudinal gradient in beta-diversity

The paper tests whether beta-diversity contributes to the latitudinal gradient in species richness by analyzing tree species data across East Asia.

Pan-genome analyses of peach and its wild relatives provide insights into the genetics of disease resistance and species adaptation

The paper performs pan-genome analysis of peach and its wild relatives to identify genetic variations related to disease resistance and high-altitude adaptation.

The soursop genome and comparative genomics of basalangiosperms provide new insights on evolutionaryincongruence

The paper presents the soursop genome and uses phylogenomic analysis to resolve angiosperm relationships, finding magnoliids as sister to monocots and eudicots.

Inhibiting TG2 sensitize lung cancer to radiotherapy through interfering TOPOIIα-mediated DNA repair

This study shows that inhibiting TG2 increases radiosensitivity in NSCLC by disrupting TOPOIIα-mediated DNA repair.

Hydraulic traits are more diverse in flowers than in leaves

The paper compares hydraulic trait diversity between flowers and leaves, finding greater diversity in flowers.