Author

F. Moreau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Boyance· 1 shared A. Coste· 1 shared A. Hessel· 1 shared A. Metais· 1 shared B. Ledoussal· 1 shared C. Amadori· 1 shared C. Batisse· 1 shared C. Berrone· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperImmunology

A. Boyance

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Biological and structural analysis of new potent Integrase-LEDGF allosteric HIV-1 inhibitors

E. Le Rouzic, D. Bonnard, F. Le Strat, C. Batisse, J. Batisse, C. Amadori, S. Chasset, S. Emiliani, B. Ledoussal, M. Ruff, F. Moreau, R. Benarous

This paper describes a new class of HIV-1 integrase-LEDGF allosteric inhibitors with potent anti-HIV activity, resistance to existing drugs, and a lead compound validated in a phase I trial.

bioRxiv · Jan 28, 2023 · PreprintMicrobiology

Phospholipid peroxidation fuels ExoU phospholipase-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology

S. Bagayoko, S.-A. Leon-Icaza, M. Pinilla, A. Hessel, K. Santoni, P.-J. Bordignon, F. Moreau, E. Eren, A. Boyance, E. Naser, L. Lefevre, C. Berrone, N. Iacobachvili, A. Metais, Y. Rombouts, , E. Meunier

This study identifies phospholipid peroxidation as a mechanism enhancing ExoU phospholipase activity, leading to cell necrosis and supporting Pseudomonas aeruginosa pathogenesis.

bioRxiv · Feb 17, 2021Immunology

Characterization of Viral Insulins Reveals White Adipose Tissue Specific Effects in Mice

M. Chrudinova, F. Moreau, H. L. Noh, T. Panikova, L. Zakova, R. H. Friedline, F. A. Valenzuela, J. K. Kim, J. Jiracek, C. R. Kahn, E. Altindis

This study characterizes double-chain viral insulin-like peptides (dcVILPs) and shows they stimulate glucose uptake in white adipose tissue in mice with higher efficacy than insulin.

bioRxiv · Aug 21, 2020Cell Biology