Author

E. Eren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

E. Meunier· 3 shared P.-J. Bordignon· 3 shared R. Planes· 3 shared A. Coste· 2 shared A. Hessel· 2 shared C. Cougoule· 2 shared K. Santoni· 2 shared M. Pinilla· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

E. Meunier

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Prebiotic gas flow environment enables isothermal nucleic acid replication

P. Schwintek, E. Eren, C. B. Mast, D. Braun

This study demonstrates that an isothermal prebiotic gas flow environment enables exponential DNA replication by concentrating nucleic acids and reducing salt concentration.

bioRxiv · Jun 13, 2024Biophysics

Novel modification of Luminex assay for characterization of extracellular vesicle populations in biofluids.

O. V. Volpert, E. Gershun, K. Elgart, V. Kalia, H. Wu, A. A. Baccarelli, E. Eren, D. Kapogiannis, A. Verma, A. Levine, E. Eitan

This paper introduces a novel Luminex-based immunoassay for multiplexed detection of EV surface proteins without requiring EV purification, demonstrating its ability to differentiate EVs from erythrocytes, macrophages, and neurons.

bioRxiv · Jan 12, 2022 · PreprintCell Biology

Phospholipid peroxidation fuels ExoU phospholipase-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology

S. Bagayoko, S.-A. Leon-Icaza, M. Pinilla, A. Hessel, K. Santoni, P.-J. Bordignon, F. Moreau, E. Eren, A. Boyance, E. Naser, L. Lefevre, C. Berrone, N. Iacobachvili, A. Metais, Y. Rombouts, , E. Meunier

This study identifies phospholipid peroxidation as a mechanism enhancing ExoU phospholipase activity, leading to cell necrosis and supporting Pseudomonas aeruginosa pathogenesis.

bioRxiv · Feb 17, 2021Immunology

Irgm2 and Gate-16 cooperatively dampen targeting of caspase-11 to Gram-negative bacterial products

E. Eren, R. Planes, S. Bagayoko, P.-J. Bordignon, K. Chaoui, A. Hessel, K. Santoni, M. Pinilla, O. Schiltz, J. C. Howard, M. Yamamoto, E. Meunier

This study identifies Irgm2 and Gate-16 as cooperative regulators that dampen non-canonical inflammasome activation by reducing caspase-11 targeting to intracellular bacteria.

bioRxiv · Mar 6, 2020Immunology

Type-3 Secretion System-induced pyroptosis protects Pseudomonas against cell-autonomous immunity

E. Eren, R. Planes, J. M. Buyck, P.-J. Bordignon, A. Colom, O. Cunrath, R. F. Dreier, J. C. Santos, V. Duplan-Eche, E. Näser, A. Peixoto, D. Bumann, C. Cougoule, A. Coste, O. Neyrolles, , E. Meunier

This study shows that Pseudomonas aeruginosa uses its Type-3 Secretion System to induce macrophage pyroptosis, escaping immune trapping, while T3SS-deficient strains are captured by inflammasome-mediated immunity.

bioRxiv · May 28, 2019 · PreprintImmunology