Author

Fangmin Yu

Weill Cornell Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 3

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Chloe Lopez-LeeiD· 2 shared Kendra Norman· 2 shared Li FaniD· 2 shared Li GaniD· 2 shared Man Ying WongiD· 2 shared Nessa R. Foxe· 2 shared Pearly Ye· 2 shared Wenjie LuoiD· 2 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Chloe Lopez-LeeORCID

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3 papers

Recent·Most cited

Perimenopause promotes neuroinflammation in select hippocampal regions in a mouse model of Alzheimers disease

Roberta Marongiu, Jimcy Platholi, Laibaik Park, Fangmin Yu, Garrett Sommer, Clara Woods, Teresa A. Milner, Michael J. Glass

This study shows that perimenopause increases Aβ aggregation and glial activation in specific hippocampal regions in female 5xFAD mice, but not cognitive deficits.

bioRxiv · Mar 14, 2025 · PreprintNeuroscience

Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

Gillian Carling, Li Fan, Nessa R. Foxe, Kendra Norman, Man Ying Wong, Daphne Zhu, Carlo Corona, Agnese Razzoli, Fangmin Yu, Allan Yarahmady, Pearly Ye, Hao Chen, Yige Huang, Sadaf Amin, Rebecca Sereda, , Li Gan

This study combines APOE4 and TREM2R47H in female tauopathy mice to identify pathways activated by AD risk factors, finding cGAS-STING signaling and microglial senescence as potential drivers.

Neuron · Sep 30, 2024Peer-reviewedNeuroscience

Sex Chromosomes and Gonads Shape the Sex-Biased Transcriptomic Landscape in Tlr7-Mediated Demyelination During Aging

Chloe Lopez-Lee, Lay Kodama, Li Fan, Man Ying Wong, Nessa R. Foxe, Laraib Jiaz, Fangmin Yu, Pearly Ye, Jingjie Zhu, Kendra Norman, Eileen Ruth S. Torres, Rachel D. Kim, Gergey Alzaem Mousa, Dena B. Dubal, Shane Antony Liddelow, , Li Gan

The paper identifies sex-biased transcriptomic responses in aged demyelination, showing Tlr7 mediates these differences through interactions with sex chromosomes and gonads.

bioRxiv · Sep 19, 2023 · PreprintNeuroscience