Author

I. N. Moore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 7 Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 11 Research Focus:host-pathogen & immune response· 10 Organism:human· 4 Organism:non-human primate· 4 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:mouse· 3

Frequent Co-Authors

M. Minai· 5 shared K. W. Bock· 4 shared B. F. Haynes· 3 shared B. M. Nagata· 3 shared C. T. DeMarco· 3 shared D. C. Montefiori· 3 shared D. Li· 3 shared D. R. Martinez· 3 shared

Activity by Year

2018-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

M. Minai

Mutual co-authors in cluster

Author profile →

11 papers

Recent·Most cited

Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates

R. D. Malewana, V. Stalls, A. May, X. Lu, D. R. Martinez, A. Schafer, D. Li, M. Barr, L. L. Sutherland, E. Lee, R. Parks, W. E. Beck, A. Newman, K. W. Bock, M. Minai, , K. O. Saunders

Non-stabilized SARS-CoV-2 Spike mRNA vaccination in macaques induces B cell lineages targeting conserved epitopes on Omicron variants or cross-neutralizing epitopes on Sarbecoviruses.

bioRxiv · Dec 18, 2023 · PreprintImmunology

Anopheles salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission

Z. R. Pala, T. L. Alves e Silva, M. Minai, B. Crews, E. Patino-Martinez, C. Carmona-Rivera, P. C. Valenzuela-Leon, I. Martin-Martin, Y. Flores-Garcia, R. E. Cachau, N. Srivastava, I. N. Moore, D. A. Alves, M. J. Kaplan, E. Fischer, , J. Vega-Rodriguez

This study shows that Anopheles salivary apyrase promotes Plasmodium transmission by modulating hemostasis during blood feeding.

bioRxiv · May 22, 2023 · PreprintMicrobiology

Commercial influenza vaccines vary in both the structural arrangements of HA complexes and in induction of antibodies to cross-reactive HA epitopes

M. L. Myers, J. R. Gallagher, A. J. Kim, W. H. Payne, K. W. Bock, U. Torian, I. N. Moore, A. K. Harris

This study examines how different structural arrangements of hemagglutinin (HA) in commercial influenza vaccines correlate with the induction of cross-reactive antibodies.

bioRxiv · Sep 22, 2022 · PreprintMicrobiology

Imbalanced immune response and dysregulation of neural functions underline fatal opportunistic encephalitis caused by astrovirus

O. A. Maximova, M. L. Weller, T. Krogmann, D. E. Sturdevant, S. Ricklefs, K. Virtaneva, C. Martens, K. Wollenberg, M. Minai, I. N. Moore, C. S. Sauter, J. N. Barker, I. Lipkin, D. Seilhean, A. Nath, J. I. Cohen

This study investigates astrovirus-induced CNS infection in immunocompromised patients, showing immune dysregulation and neural dysfunction similar to HIV.

bioRxiv · Aug 20, 2022 · PreprintMicrobiology

Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques

C. Le Nouen, C. E. Nelson, X. Liu, H.-S. Park, Y. Matsuoka, C. Luongo, C. Santos, L. Yang, R. Herbert, A. Castens, I. N. Moore, T. Wilder-Kofie, R. Moore, A. Walker, P. Zhang, , U. J. Buchholz

This study evaluates an intranasal parainfluenza virus-vectored SARS-CoV-2 vaccine in macaques, showing it induces mucosal and systemic immunity and protects against viral challenge.

bioRxiv · May 21, 2022Immunology

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

D. Li, D. R. Martinez, A. Schäfer, H. Chen, M. Barr, L. L. Sutherland, E. Lee, R. Parks, D. Mielke, W. Edwards, A. Newman, K. W. Bock, M. Minai, B. M. Nagata, M. Gagne, , B. F. Haynes

This study shows a nanoparticle vaccine induces broad neutralizing antibodies against multiple SARS-CoV-2 variants and protects non-human primates and mice from viral challenges.

bioRxiv · Jan 26, 2022Immunology

Eosinophils are an integral component of the pulmonary granulocyte response in Tuberculosis and promote host resistance in mice

A. C. Bohrer, E. Castro, Z. Hu, A. T. L. Queiroz, C. E. Tocheny, M. Assmann, S. Sakai, C. Nelson, P. J. Baker, H. Ma, L. Wang, W. Zilu, E. du Bruyn, C. Riou, K. D. Kauffman, , K. D. Mayer-Barber

This study shows eosinophils are recruited to tuberculosis-infected lung tissue in mice and contribute to host resistance against Mtb infection.

bioRxiv · May 29, 2021Immunology

SARS-CoV-2 vaccination induces neutralizing antibodies against pandemic and pre-emergent SARS-related coronaviruses in monkeys

K. O. Saunders, E. Lee, R. Parks, D. R. Martinez, D. Li, H. Chen, R. J. Edwards, S. M. C. Gobeil, M. Barr, K. Mansouri, S. M. Alam, L. L. Sutherland, F. Cai, A. Sanzone, M. Berry, , B. F. Haynes

This study shows that SARS-CoV-2 vaccines induce neutralizing antibodies against SARS-CoV-1, SARS-CoV-2, and batCoVs in monkeys.

bioRxiv · Feb 17, 2021 · PreprintImmunology

mRNA-1273 efficacy in a severe COVID-19 model: attenuated activation of pulmonary immune cells after challenge

M. Meyer, Y. Wang, D. Edwards, G. R. Smith, A. B. Rubenstein, P. Ramanathan, C. E. Mire, C. Pietzsch, X. Chen, Y. Ge, W. S. Cheng, C. Henry, A. Woods, L. Ma, G. B. E. Stewart-Jones, , A. Bukreyev

This study evaluates mRNA-1273 vaccine efficacy in hamsters, showing reduced pulmonary immune activation and improved disease outcomes after prime-boost vaccination.

bioRxiv · Jan 25, 2021 · PreprintImmunology

Clinical Characterization of Host Response to Simian Hemorrhagic Fever Virus Infection in Permissive and Refractory Hosts: A Model for Determining Mechanisms of VHF Pathogenesis

J. P. Cornish, I. N. Moore, D. L. Perry, A. Lara, M. Minai, D. Promeneur, K. R. Hagan, K. Virtaneva, M. Paneru, C. Buechler, D. H. O'Connor, A. L. Bailey, K. Cooper, S. Mazur, J. G. Bernbaum, , R. F. Johnson

This paper compares host responses to SHFV infection in patas and rhesus monkeys, identifying overlapping and species-specific cytokine and immune cell changes that may drive hemorrhagic fever pathogenesis.

bioRxiv · Oct 31, 2018Immunology

Prolonged culture of primary human keratinocytes isolated from suction blisters

E. D. Anderson, I. Sastalla, N. J. Earland, M. Mahnaz, I. N. Moore, F. Otaizo-Carrasquero, T. G. Myers, C. A. Myles, S. K. Datta, I. A. Myles

This study shows that the ROCK inhibitor Y-27632 prolongs the culture of primary human keratinocytes isolated from suction blisters, delaying differentiation and enabling longer-term functional analysis.

bioRxiv · May 29, 2018Cell Biology