Author

Hideru Obinata

Gunma University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Abdülkadir ElmasiD· 1 shared Aiko Tsuchida· 1 shared Akimitsu KonishiiD· 1 shared D.K. InaokaiD· 1 shared Eizo TakashimaiD· 1 shared Fuyuki TokumasuiD· 1 shared Hideo ShindouiD· 1 shared Hillary M. LaydeniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenomics

Abdülkadir ElmasORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Plasmodium falciparum diacylglycerol acyltransferase maintains phospholipid homeostasis to regulate sexual differentiation, ER stress, and cytoadhesion

Minako Yoshida, Junpei Fukumoto, Shinya Miyazaki, Megumi Tanaka, Suzumi M. Tokuoka, Hideru Obinata, Takaya Sakura, Yoko Onizuka, D.K. Inaoka, Kiyoshi Kita, Kazuhide Yahata, Eizo Takashima, Hideo Shindou, Fuyuki Tokumasu

This study shows that PfDGAT is essential for Plasmodium falciparum survival by maintaining phospholipid homeostasis, regulating sexual differentiation, ER stress, and cytoadhesion.

bioRxiv · Oct 10, 2025 · PreprintMicrobiology

Expression-Driven Genetic Dependency Reveals Targets for Precision Medicine

Abdülkadir Elmas, Hillary M. Layden, Jacob D. Ellis, Luke N. Bartlett, Xian Zhao, Reika Kawabata‐Iwakawa, Hideru Obinata, Scott W. Hiebert, Kuan‐lin Huang

The paper identifies expression-driven genetic dependency targets for precision oncology using a Bayesian approach, revealing new druggable genes and validating their therapeutic potential.

bioRxiv · Oct 17, 2024 · PreprintGenomics

Branched-chain amino acid metabolism is a crucial modulator of cellular senescence

Yuma Aramaki, Kazuki Irie, Hideru Obinata, Shinya Honda, Takuro Horii, Satoko Arakawa, Aiko Tsuchida, Junki Hoshino, Ryosuke Kobayashi, Takashi Izumi, Izuho Hatada, Shigeomi Shimizu, Yoji Andrew Minamishima, Akimitsu Konishi

This study shows that changes in branched-chain amino acid (BCAA) metabolism, specifically reduced BCAT2 activity, drive cellular senescence in cultured cells and mice, and link aging to altered BCAA metabolism in humans.

bioRxiv · Sep 10, 2024 · PreprintCell Biology