Author

Huinan Li

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Adam J. LittermaniD· 1 shared Elise MarsaniD· 1 shared Eric Jinsheng HuangiD· 1 shared Erik M. UllianiD· 1 shared Gunisha AroraiD· 1 shared Joseph R. KlimiD· 1 shared Kaivalya ShevadeiD· 1 shared Kun LengiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Adam J. LittermanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

SAMHD1 Knockout iPSC model enables high lenti-viral transduction in myeloid cell types

Huinan Li, Maliha Afroze, Gunisha Arora, Scot Federman, Kaivalya Shevade, Yeqing Angela Yang, Phuong Nguyen, Rustam Esanov, Laralynne Przybyla, Adam J. Litterman, Shawn Shafer

The paper develops a SAMHD1 knockout iPSC model that enhances lentiviral transduction efficiency in myeloid cells, enabling better functional genomics studies in innate immunity and inflammatory diseases.

bioRxiv · Feb 4, 2025 · PreprintCell Biology

Granulin Loss of Function in Human Mature Brain Organoids Implicates Astrocytes in TDP-43 Pathology

Martina de Majo, Mark Koontz, Elise Marsan, Nir Salinas, Marina Ramsey, Yien–Ming Kuo, Kyounghee Seo, Huinan Li, Nina M. Dräger, Kun Leng, Santiago L. Gonzales, Michael Kurnellas, Yuichiro Miyaoka, Joseph R. Klim, Martin Kampmann, , Erik M. Ullian

The paper shows that loss of GRN in human brain organoids leads to TDP-43 pathology, driven by astrocytes, and can be rescued by progranulin.

Stem Cell Reports · Feb 23, 2023Peer-reviewedNeuroscience