A conserved mechanism for regulation of mtDNA copy number in eukaryotes
Flora McNulty, Andrew M. Shaw, Amy Shepherd, Jacqueline Tait-Mulder, Hannah Mearns, Ignacio Fernandez-Guerrero, Peggy Paschke, Elisabetta Tolla, Zaniah N. Gonzalez-Galofre, Christina Wijo, Morgan J McIntosh, Sérgio Lilla, Graeme Clark, Alejandro Huerta Uribe, David P. Sumpton, , Payam A. Gammage
The paper identifies a conserved mechanism regulating mtDNA copy number through compartmentalization of redox co-factors across eukaryotes.
bioRxiv · May 31, 2026 · PreprintCell Biology