Author

A. Solomon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 7 Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Approach:statistical model· 5 Assay:scRNA-seq· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2

Frequent Co-Authors

R. Avraham· 4 shared D. Hoffman· 3 shared N. Bossel Ben-Moshe· 3 shared S. Trzebanski· 3 shared D. Yehezkel· 2 shared G. Rosenberg· 2 shared J.-S. Kim· 2 shared L. Shlush· 2 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersImmunology

R. Avraham

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Early and Delayed STAT1-Dependent Responses Drive Local Trained Immunity of Macrophages in the Spleen

A. Solomon, N. Bossel Ben-Moshe, D. Hoffman, S. Trzebanski, D. Yehezkel, L. Vainman, M. G. Netea, R. Avraham

This study identifies early and delayed STAT1-dependent responses in splenic macrophages that drive trained immunity, enhancing protection against Salmonella Typhimurium infection.

bioRxiv · Jul 19, 2024Immunology

Monocyte-derived microglia with Dnmt3a mutation cause motor pathology in aging mice

J.-S. Kim, S. Trzebanski, S.-H. Shin, N. C. Ilani, N. Kaushansky, M. Scheller, A. Solomon, Z. Liu, O. Aust, S. Boura-Halfon, L. Amann, M. Prinz, F. Ginhoux, R. Avraham, C. Mueller-Tidow, , S. Jung

This study shows that monocyte-derived microglia with a Dnmt3a mutation cause motor deficits in aging mice, resembling Parkinsonian disorders.

bioRxiv · Nov 16, 2023Immunology

Murine GMP- and MDP-derived classical monocytes have distinct functions and fates

S. Trzebanski, J.-S. Kim, N. Larrossi, D. Kancheva, J. Bastos, M. Haddad, D. Aizik, J. Kralova, M. Gross-Vered, S. Boura-Halfon, T. Lapidot, R. Alon, K. Movahedi, S. Jung, E. Sivan, , A. Raanan

This study identifies distinct functions and fates of murine classical monocytes derived from GMP and MDP, showing differential contributions to tissue macrophage populations.

bioRxiv · Jul 29, 2023Immunology

Paired single-cell host profiling with multiplex-tagged bacterial mutants reveals intracellular virulence-immune networks

O. Heyman, D. Yehezkel, N. Blumberger, G. Rosenberg, C. Ciolli Mattioli, A. Solomon, D. Hoffman, N. Bossel Ben-Moshe, R. Avraham

The paper introduces scPAIR-seq to simultaneously analyze host and bacterial factors during infection, revealing virulence-immune networks in Salmonella Typhimurium.

bioRxiv · Mar 6, 2022Microbiology

Inflammatory signals from fatty bone marrow supports the early stages of DNMT3a driven clonal hematopoiesis

N. Zioni, A. Bercovich, N. Chapal-Ilani, A. Solomon, E. Petrovich, M. .Sacma, H. Geiger, M. Scheller, C. Müller-Tidow, D. Lipka, E. Shlush, M. Minden, N. Kaushansky, L. Shlush

This study shows that fatty bone marrow (FBM) promotes DNMT3A-driven clonal hematopoiesis by enhancing inflammatory signals like IL-6, which can be inhibited by blocking the IL-6 receptor.

bioRxiv · Jan 13, 2022Cancer Biology

Uncovering the modified immunopeptidome reveals insights into principles of PTM-driven antigenicity

A. Kacen, A. Javitt, M. P. Kramer, D. Morgenstern, T. Tsaban, A. Solomon, G. C. Teo, F. da Veiga Leprevost, E. Barnea, F. Yu, A. Admon, L. Eisenbach, G. Cafri, O. Schueler-Furman, Y. Levin, , Y. Merbl

The paper identifies thousands of novel cancer-specific antigens by analyzing PTMs in immunopeptidomics data from multiple sources and reveals their impact on HLA binding and TCR recognition.

bioRxiv · Apr 10, 2021 · PreprintCancer Biology

scRNA-seq Reveals A Macrophage Subset That Provides A Splenic Replication Niche For Intracellular Salmonella

D. Hoffman, R. Avraham, Y. Tevet, G. Rosenberg, L. Vainman, A. Solomon, S. Hen-Avivi, N. Bossel Ben-Moshe

The paper uses scRNA-seq to identify a macrophage subset in mice that supports intracellular Salmonella replication in the spleen, revealing a cell-type specific host-pathogen interaction.

bioRxiv · Jan 4, 2021Immunology

Active Trachoma Cases In The Solomon Islands Have Varied Polymicrobial Community Structures But Do Not Associate With Individual Non-Chlamydial Pathogens Of The Eye

R. Butcher, O. Sokana, K. Jack, E. Kalae, L. Sui, C. Russell, J. Houghton, C. Palmer, M. J. Holland, R. Le Mesurier, A. Solomon, D. Mabey, C. h. Roberts

The paper investigates whether active trachoma in the Solomon Islands is linked to non-chlamydial pathogens or polymicrobial dysbiosis, finding no significant association with individual pathogens but noting inter-individual microbiome variation.

bioRxiv · Oct 10, 2017Microbiology