Author

J. P. Dufour

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:non-human primate· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

P. P. Aye· 3 shared F. Schiro· 2 shared J. Rappaport· 2 shared K. Russell-Lodrigue· 2 shared R. P. Bohm· 2 shared R. V. Blair· 2 shared A. B. Ward· 1 shared A. Kaur· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

P. P. Aye

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection

A. Melton, L. A. Rowe, T. Penney, C. Krzykwa, K. Goff, S. E. Scheuermann, H. J. Melton, K. Williams, N. Golden, K. Moore Green, B. Smith, K. Russell-Lodrigue, J. P. Dufour, L. A. Doyle-Meyers, F. Schiro, , N. J. Maness

This study examines how SIV-induced immunodeficiency affects SARS-CoV-2 infection in macaques, finding that while immune responses are impaired, viral kinetics and evolution remain unchanged.

bioRxiv · Nov 15, 2023 · PreprintImmunology

Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

J. H. Lee, H. J. Sutton, C. A. Cottrell, I. Phung, G. Ozorowski, L. M. Sewall, R. Nedellec, C. Nakao, M. Silva, S. T. Richey, J. L. Torres, W.-H. Lee, E. Georgeson, M. Kubitz, S. Hodges, , S. Crotty

This study shows that germinal center B cells can persist and continue to mutate for 29 weeks after a single immunization, leading to long-lasting antibody responses.

bioRxiv · Dec 20, 2021 · PreprintImmunology

An Orally Available Cathepsin L Inhibitor Protects Lungs Against SARS-CoV-2-Induced Diffuse Alveolar Damage in African Green Monkeys

F. W. Frueh, D. C. Maneval, R. P. Bohm, J. P. Dufour, R. V. Blair, S. Simpson, K. Powell, P. P. Aye, N. A. Golden, C. J. ROY, S. Spencer, K. Russell-Lodrigue, K. S. Plante, J. A. Plante, J. H. McKerrow, J. Rappaport

This study shows that the orally available cathepsin L inhibitor K777 reduces SARS-CoV-2-induced lung damage in African green monkeys.

bioRxiv · Jul 20, 2021 · PreprintImmunology