Author

Jeehae Han

Albert Einstein College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Yousin SuhiD· 2 shared Aaron J. WolfeiD· 1 shared Adam D. HudginsiD· 1 shared Advait AthreyaiD· 1 shared Agnieszka D’Antonio‐ChronowskaiD· 1 shared Alexis Pope· 1 shared Alice E. Zemljic‐HarpfiD· 1 shared Amir Gamliel· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Yousin SuhORCID

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Author profile →

3 papers

Recent·Most cited

Recruitment of CTCF to the SIRT1 promoter after Oxidative Stress mediates Cardioprotective Transcription

Tobias Wagner, Priyanka Priyanka, Rudi Micheletti, Meyer J. Friedman, Sreejith J. Nair, Amir Gamliel, Havilah Taylor, Xiaoyuan Song, Miook Cho, Soohwan Oh, Wenbo Li, Jeehae Han, Kenneth A. Ohgi, Madeline Abrass, Agnieszka D’Antonio‐Chronowska, , Yousin Suh

The paper shows that phosphorylated CTCF binds the SIRT1 promoter under oxidative stress, activating a cardioprotective transcriptional program in cardiomyocytes.

bioRxiv · May 17, 2024 · PreprintCell Biology

A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A

Matthew A. Simon, Jiping Yang, Jonathan Gigas, Eric J. Earley, Eric C. Hillpot, Lei Justan Zhang, Maria Zagorulya, Greg Tombline, Michael B. Gilbert, Samantha L. Yuen, Alexis Pope, Michael Van Meter, Stephan Emmrich, Denis Firsanov, Advait Athreya, , Vera A. Gorbunova

The paper identifies a SIRT6 variant enriched in centenarians that improves genome stability through enhanced mADPr activity and interaction with Lamin A.

The EMBO Journal · Oct 10, 2022Peer-reviewedMolecular Biology

Protein kinase C is a key target for attenuation of Leigh syndrome by rapamycin

Miguel Martín‐Pérez, Anthony S. Grillo, Takashi K. Ito, Anthony S. Valente, Jeehae Han, Samuel W. Entwisle, Heather Z Huang, Dayae Kim, Masanao Yajima, Matt R. Kaeberlein, Judit Villén

The paper identifies PKC as a therapeutic target for treating mitochondrial disease by analyzing proteomic and phosphoproteomic changes in a mouse model of Leigh syndrome.

Nature Metabolism · Dec 14, 2020Peer-reviewedNeuroscience