Author

Julien Delile

The Francis Crick Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 4

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Research Focus:cell type annotation· 4 Organism:mouse· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

James BriscoeiD· 3 shared Andreas SagneriD· 2 shared Manuela MelchiondaiD· 2 shared Ailin Leticia BuzziiD· 1 shared Alexandre P ThieryiD· 1 shared Amelia Edwards· 1 shared Andrea StreitiD· 1 shared Bennett G. NovitchiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

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10 top collaborators · 21 mutual co-author links

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3 shared papersDevelopmental Biology

James BriscoeORCID

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4 papers

Recent·Most cited

Sox8 remodels the cranial ectoderm to generate the ear

Ailin Leticia Buzzi, Jingchen Chen, Alexandre P Thiery, Julien Delile, Andrea Streit

The paper identifies Sox8 as a key transcription factor that remodels cranial ectoderm to generate ear progenitors and activate ear development programs.

Proceedings of the National Academy of Sciences · Jul 8, 2022Peer-reviewedDevelopmental Biology

Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak.

Kenzo Ivanovitch, Pablo Soro-Barrio, Probir Chakravarty, Rebecca A. Jones, Donald M. Bell, Seyedeh Neda Mousavy-Gharavy, Despina Stamataki, Julien Delile, James C. Smith, James Briscoe

The paper identifies spatial and molecular differences in cardiac progenitor origins in mouse embryos, showing distinct regions of the primitive streak contribute to different heart structures.

PLoS Biology · May 17, 2021Peer-reviewedDevelopmental Biology

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

Julien Delile, Teresa Rayón, Manuela Melchionda, Amelia Edwards, James Briscoe, Andreas Sagner

scRNA-seq of 21465 mouse neural tube cells (e9.5-e13.5) maps spinal progenitor and neuron types, validates new subtype markers, and reveals temporally staged transcription-factor modules.

Development · Mar 7, 2019Peer-reviewedDevelopmental Biology✦ In-depth digest

Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

Andreas Sagner, Zachary B. Gaber, Julien Delile, Jennifer H. Kong, David L. Rousso, Caroline Alayne Pearson, Steven E. Weicksel, Manuela Melchionda, S. Neda Mousavy Gharavy, James Briscoe, Bennett G. Novitch

The paper uses single cell transcriptomics to study Olig2 and Hes regulatory dynamics during motor neuron differentiation, revealing Olig2's role in repressing Hes5 and coordinating differentiation timing.

PLoS Biology · Feb 1, 2018Peer-reviewedDevelopmental Biology