Author

K. Hoshino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:multiple species· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Miyake· 2 shared T. Kaisho· 2 shared Y. Fukuda-Ohta· 2 shared A. Goto· 1 shared A. Yamamoto· 1 shared C. Nakai· 1 shared C. Okamoto· 1 shared D. Okuzaki· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

K. Miyake

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Latent taste diversity revealed by a vertebrate-wide catalogue of T1R receptors

H. Nishihara, Y. Toda, T. Kuramoto, K. Kamohara, A. Goto, K. Hoshino, S. Okada, S. Kuraku, M. Okabe, Y. Ishimaru

The paper identifies five new TAS1R receptors in vertebrates, revealing greater taste receptor diversity than previously thought and their functional roles in ligand recognition.

Nature Ecology & Evolution · Dec 13, 2023Peer-reviewedEvolutionary Biology

A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages

I. Sasaki, Y. Fukuda-Ohta, C. Nakai, N. Wakaki-Nishiyama, C. Okamoto, T. Orimo, D. Okuzaki, S. Morita, S. Kaji, Y. Furuta, H. Hemmi, T. Kato, A. Yamamoto, T. Tanaka, K. Hoshino, , T. Kaisho

The paper shows that IRE1α is essential for CTB and CT-induced IL-1β production in tissue-resident macrophages via NLRP3 and pyrin inflammasomes.

bioRxiv · Jul 6, 2023 · PreprintImmunology

Microbiome ssRNA as an environmental cue to activate TLR13-dependent tissue-protective programs in CD5Lhi hepatic macrophages

R. Sato, K. Liu, T. Shibata, K. Hoshino, K. Yamaguchi, T. Miyazaki, R. Hiranuma, R. Fukui, Y. Motoi, Y. Fukuda-Ohta, Y. Zhang, T. Reuter, Y. Ishida, T. Kondo, T. Chiba, , K. MIYAKE

The paper shows that microbiome ssRNA activates TLR13 in hepatic macrophages to drive tissue-protective responses, leading to resistance against acute liver injury in Rnaset2-/- mice.

bioRxiv · May 11, 2023 · PreprintImmunology