Author
K. M. Murphy
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 16 mutual co-author links8 papers
Recent·Most cited
WDFY4 deficiency in NOD mice abrogates autoimmune diabetes and insulitis
S. T. Ferris, J. Chen, R. A. Ohara, R. Wu, S. Kim, T. Liu, T. Murphy, K. M. Murphy
This study shows that WDFY4 deficiency in NOD mice prevents autoimmune diabetes by blocking CD8 T cell priming, while preserving CD4 T cell activation and islet infiltration.
bioRxiv · Sep 2, 2022 · PreprintImmunology
A dolabralexin-deficient mutant provides insight into specialized diterpenoid metabolism in maize (Zea mays).
K. M. Murphy, T. Dowd, A. Khalil, S. N. Char, B. Yang, B. J. Endelman, P. M. Shih, C. N. Topp, E. A. Schmelz, P. Zerbe
The paper identifies ZmKSL4 as the diterpene synthase for dolabralexin biosynthesis in maize and shows its role in root architecture under water deficit.
bioRxiv · Jul 21, 2022 · PreprintPlant Biology
The conventional dendritic cell 1 subset primes CD8+ T cells and traffics tumor antigen to drive anti-tumor immunity in the brain
J. A. Bowman-Kirigin, B. T. Saunders, R. Desai, A. Z. Wang, M. O. Schaettler, C. J. Liu, A. J. Livingstone, D. K. Kobayashi, V. Durai, N. M. Kretzer, G. J. Zipfel, E. C. Leuthardt, J. W. Osbun, M. R. Chicoine, A. H. Kim, , G. P. Dunn
The paper identifies cDC1's role in priming CD8+ T cells and trafficking tumor antigens to drive anti-tumor immunity in the brain.
bioRxiv · Sep 13, 2021Immunology
cDC1 Coordinate Innate and Adaptive Responses in the Omentum required for T cell Priming and Memory
D. A. Christian, T. A. Adams, T. E. Smith, L. A. Shallberg, D. J. Theisen, A. T. Phan, M. Abraha, J. Perry, G. Ruthel, J. T. Clark, K. M. Murphy, R. M. Kedl, C. A. Hunter
This study shows that cDC1 in the omentum support T cell expansion and survival during Toxoplasma gondii infection, not T cell priming.
bioRxiv · Jul 21, 2020Immunology
Genetic elucidation of complex biochemical traits mediating maize innate immunity
Y. Ding, P. R. Weckwerth, E. Poretsky, K. M. Murphy, J. Sims, E. Saldivar, S. A. Christensen, S. N. Char, B. Yang, A.-d. Tong, Z. Shen, K. Kremling, E. S. Buckler, T. J. Y. Kono, D. R. Nelson, , A. Huffaker
The paper identifies ten genes in maize that drive antibiotic biosynthesis, revealing a resilient pathway critical for disease resistance.
bioRxiv · Mar 4, 2020 · PreprintPlant Biology
Toxoplasma gondii infection drives conversion of NK Cells into ILC1s
E. Park, S. Patel, Q. Wang, P. Andhey, K. Zaitsev, S. Porter, M. Hershey, M. Bern, B. Plougastel-Douglas, P. Collins, M. Colonna, K. M. Murphy, E. Oltz, M. Artyomov, L. D. Sibley, W. M. Yokoyama
This study shows Toxoplasma gondii infection converts NK cells into ILC1-like cells that persist and circulate independently of infection.
bioRxiv · May 17, 2019Immunology