Author

O. Bayraktar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Organism:human· 6 Research Focus:differential expression· 5 Assay:scRNA-seq· 5 Approach:statistical model· 5 Research Focus:gene regulatory network inference· 3 Approach:deep learning· 2 Approach:experimental assay· 2

Frequent Co-Authors

K. Polanski· 4 shared K. Roberts· 4 shared L. Mamanova· 4 shared R. Elmentaite· 4 shared E. Tuck· 3 shared R. A. Barker· 3 shared S. A. Teichmann· 3 shared X. He· 3 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersImmunology

K. Polanski

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Single cell transcriptomics reveals chondrocyte differentiation dynamics in vivo and in vitro

J. E. G. Lawrence, S. Woods, K. Roberts, D. N. Sumanaweera, P. Balogh, A. V. Predeus, P. He, T. Li, K. Polanski, E. Prigmore, E. Tuck, L. Mamanova, D. Zhou, S. Webb, L. Jardine, , S. Teichmann

This study uses single-cell transcriptomics to compare in vitro and in vivo chondrocyte differentiation, identifies off-target differentiation, and improves in vitro protocols by inhibiting FOXO1.

bioRxiv · Dec 20, 2023Bioengineering

A spatial human thymus cell atlas mapped to a continuous tissue axis

N. Yayon, V. R. Kedlian, L. Boehme, C. Suo, B. Wachter, R. T. Beuschel, O. Amsalem, K. Polanski, S. Koplev, E. Tuck, E. Dann, J. Van Hulle, S. Perera, T. Putteman, A. V. Predeus, , Tag

The paper maps the spatial organization of the human thymus across developmental stages using a multimodal atlas and identifies key cellular and molecular features of T cell development.

bioRxiv · Oct 25, 2023Immunology

Cross-tissue immune cell analysis reveals tissue-specific adaptations and clonal architecture across the human body

C. Dominguez Conde, T. Gomes, L. B. Jarvis, C. Xu, S. Howlett, D. Rainbow, O. Suchanek, H. King, L. Mamanova, K. Polanski, N. Huang, E. Fasouli, K. Mahbubani, M. Prete, E. Tuck, , S. A. Teichmann

The paper analyzes immune cell diversity across 15 human tissues using single-cell RNA sequencing and VDJ sequencing, revealing tissue-specific features and clonal architecture of T and B cells.

bioRxiv · Apr 28, 2021Immunology

Cells of the human intestinal tract mapped across space and time

R. Elmentaite, N. Kumasaka, H. W. King, K. Roberts, M. Dabrowska, S. Pritchard, L. Bolt, S. F. Vieira, L. Mamanova, N. Huang, I. Goh Kai'En, E. Stephenson, J. Engelbert, R. A. Botting, A. Fleming, , S. A. Teichmann

The paper maps human intestinal cell lineages across development and disease, identifying new cell types and functions related to inflammation and immunity.

bioRxiv · Apr 7, 2021Cell Biology

Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

G. Kildisiute, W. M. Kholosy, M. D. Young, K. Roberts, R. Elmentaite, S. R. van Hooff, E. Khabirova, A. Piapi, C. Thevanesan, E. Bugallo Blanco, C. Burke, L. Mamanova, P. Lijnzaad, T. Margaritis, F. C. P. Holstege, , S. Behjati

The paper compares tumor and normal single-cell mRNA data to show neuroblastoma cells resemble fetal sympathoblasts across diverse samples.

bioRxiv · Jun 22, 2020Cancer Biology

Single-cell sequencing of developing human gut reveals transcriptional links to childhood Crohns disease

R. Elmentaite, A. Ross, K. R. James, D. Ortmann, T. Gomes, K. Roberts, K. Nayak, L. Tuck, O. Bayraktar, R. Heuschkel, L. Vallier, S. A. Teichmann, M. Zilbauer

The paper maps the developing human gut at 6-10 weeks post-conception using single-cell sequencing and links fetal transcriptional patterns to childhood Crohn's disease.

bioRxiv · Feb 6, 2020Cell Biology