Author

L.-M. Postovit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

G. M. Siegers· 2 shared I. Dutta· 2 shared I. Topisirovic· 2 shared J. Liu· 2 shared J. Schueler· 2 shared K. Tandoc· 2 shared L. Lee· 2 shared M. Jewer· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCancer Biology

G. M. Siegers

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4 papers

Recent·Most cited

Epigenetic coordination of transcriptional and translational programs in hypoxia

K. Watt, B. Dauber, K. J. Szkop, L. Lee, P. Jovanovic, S. Chen, R. Palia, J. A. Vassalakis, T. T. Cooper, D. Papadopoli, L. Masvidal, M. Jewer, K. Tandoc, H. Plummer, G. A. Lajoie, , L.-M. Postovit

The paper shows hypoxia induces TSS switching via H3K4me3 changes, altering translation of key metabolic genes like PDK1.

bioRxiv · Sep 16, 2023 · PreprintCancer Biology

Docosahexaenoic acid significantly reduces tumor cell growth in preclinical models of ovarian cancer

O. Bilyk, B. Hamedi, I. Dutta, M. Newell, A. B. Bukhari, A. M. Gamper, R. C. McVea, J. Liu, J. Schueler, G. M. Siegers, C. J. Field, L.-M. Postovit

This study shows that docosahexaenoic acid (DHA) enhances the anti-cancer effects of carboplatin in ovarian cancer models, reducing tumor growth and improving survival.

bioRxiv · Nov 10, 2020Cancer Biology

Genome profiles of lymphovascular breast cancer cells reveal multiple clonally differentiated outcomes with multi-regional LCM and G&T-seq

Z. Zhu, W. Wang, F. Lin, T. Jordan, G. Li, S. Silverman, S. Qiu, A. A. Joy, C. Chen, D. Hockley, X. Zhang, Q. Zhou, L.-M. Postovit, X. Zhang, Y. Hou, , G. K.-S. Wong

This study isolates lymphovascular breast cancer cells using LCM and G&T-seq to identify three distinct clonal pathways associated with different survival outcomes and ribosomal protein downregulation as a poor prognosis marker.

bioRxiv · Feb 1, 2020Cancer Biology

Translational control of breast cancer plasticity

M. Jewer, L. Lee, G. Zhang, J. Liu, S. D. Findlay, K. M. Vincent, K. Tandoc, D. Dieters-Castator, D. F. Quail, I. Dutta, M. Coatham, Z. Xu, B.-J. Guan, M. Hatzoglou, A. Brumwell, , L.-M. Postovit

The paper identifies hypoxia and drug-induced translational activation of NANOG, SNAIL, and NODAL isoforms that drive breast cancer plasticity and stem-cell-like phenotypes, with potential therapeutic implications.

bioRxiv · Apr 2, 2019Cancer Biology