Author

Kyle J. Schaefbauer

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 2 Organism:zebrafish· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

ANDREW HAR LIMPERiD· 2 shared Karl J. ClarkiD· 2 shared Malay ChoudhuryiD· 2 shared Stephen Carl EkkeriD· 2 shared Alexey V. DvornikoviD· 1 shared Alvin C. H. MaiD· 1 shared Arun K. Sharma· 1 shared Camden L. DabyiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

ANDREW HAR LIMPERORCID

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Author profile →

4 papers

Recent·Most cited

Targeting the DNA damage repair protein RAD51 alters fibroblast metabolism and enhances apoptosis in pulmonary fibrosis

Rahul Kumar Maurya, Arun K. Sharma, Kyle J. Schaefbauer, Lina Ma, Jeffrey R. Koenitzer, ANDREW HAR LIMPER, Malay Choudhury

This study shows that inhibiting RAD51 in fibroblasts reduces fibrosis by promoting apoptosis and metabolic changes.

bioRxiv · Apr 4, 2026 · PreprintCell Biology

Targeting Pulmonary Fibrosis by SLC1A5 dependent Glutamine Transport Blockade

Malay Choudhury, Kyle J. Schaefbauer, Theodore J. Kottom, Eunhee S. Yi, Daniel J. Tschumperlin, ANDREW HAR LIMPER

This study shows that inhibiting SLC1A5, a glutamine transporter, reduces fibrosis by altering fibroblast metabolism and function in a mouse model of lung fibrosis.

American Journal of Respiratory Cell and Molecular Biology · Jul 17, 2023Peer-reviewedMolecular Biology

The Vertebrate Codex Gene Breaking Protein Trap Library For Genomic Discovery and Disease Modeling Applications

Noriko Ichino, MaKayla R. Serres, Rhianna M. Urban, Mark D. Urban, Kyle J. Schaefbauer, Lauren E Greif, Gaurav K. Varshney, Kimberly J. Skuster, Melissa S. McNulty, Camden L. Daby, Ying Wāng, Hsin‐Kai Liao, Suzan El‐Rass, Yonghe Ding, Weibin Liu, , Stephen Carl Ekker

The paper describes a zebrafish gene break transposon library for genomic discovery and disease modeling, identifying novel gene expression patterns and generating models for human disease loci.

bioRxiv · May 7, 2019 · PreprintGenomics

Toward Precision Molecular Surgery: Robust, Selective Induction of Microhomology-mediated End Joining in vivo

Hirotaka Ata, Thomas L. Ekstrom, Gabriel Martínez‐Gálvez, Carla M. Mann, Alexey V. Dvornikov, Kyle J. Schaefbauer, Alvin C. H. Ma, Drena L Dobbs, Karl J. Clark, Stephen Carl Ekker

This paper demonstrates that inducing Microhomology-mediated End Joining (MMEJ) in vivo can generate highly homogeneous mutant alleles, with a novel algorithm provided for predicting MMEJ-inducing sites.

bioRxiv · Apr 16, 2018 · PreprintMolecular Biology