Author

L. Hua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Plant Biology· 3 Biochemistry· 2 Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

J. Liu· 2 shared J. M. Hibberd· 2 shared J. Shi· 2 shared L. Xu· 2 shared W. Zheng· 2 shared X. Zhang· 2 shared X. ZhangiD· 2 shared Y. Wang· 2 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

J. Liu

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

A novel ilarvirus protein is expressed via stop codon readthrough and suppresses RDR6-dependent RNA silencing

N. Lukhovitskaya, A. Firth, K. Brown, L. Hua, A. Pate, J. Carr

This study identifies a novel ilarvirus protein, CP-RT, produced via stop codon readthrough, which suppresses RNA silencing and is essential for persistent infection.

bioRxiv · Feb 8, 2024Plant Biology

A temperate Siphoviridae bacteriophage isolate from Siberian tiger enhances the virulence of Methicillin-resistant Staphylococcus aureus through distinct mechanisms

D. Yang, S. Wang, E. Sun, Y. Chen, L. Hua, R. Zhou, H. Chen, Z. Peng, B. Wu

This study isolates a temperate Siphoviridae bacteriophage from a Siberian tiger that enhances MRSA virulence through gene upregulation without carrying virulence or resistance genes.

bioRxiv · May 3, 2021Microbiology

The bundle sheath of rice is conditioned to play an active role in water transport as well as sulfur assimilation and jasmonic acid synthesis

L. Hua, S. R. Stevenson, I. Reyna-Llorens, H. Xiong, S. Kopriva, J. M. Hibberd

The paper identifies gene expression patterns in rice bundle sheath cells, showing specialization in water transport, sulfur assimilation, and jasmonic acid synthesis, with conservation across C3 species.

bioRxiv · Apr 16, 2021Plant Biology

Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis

H. Wang, M. Xu, C. A. Engelhart, X. Zhang, B. Yan, M. Pan, Y. Xu, S. Fan, R. Liu, L. Xu, L. Hua, D. Schnappinger, S. Chen

The paper identifies PF-3845 as a novel inhibitor of Mycobacterium tuberculosis PheRS, showing selectivity over human PheRS and potential as an antibiotic lead.

bioRxiv · Oct 27, 2020Biochemistry

Development of a simple in vitro assay to identify and evaluate nucleotide analogs against SARS-CoV-2 RNA-dependent RNA polymerase

G. Lu, X. Zhang, W. Zheng, J. Sun, L. Hua, L. Xu, X.-j. Chu, S. Ding, W. Xiong

This paper develops an in vitro assay to evaluate nucleotide analogs against SARS-CoV-2 RdRp, showing varying incorporation efficiencies and chain termination effects.

bioRxiv · Jul 16, 2020Biochemistry

Binding Ability Prediction between Spike Protein and Human ACE2 Reveals the Adaptive Strategy of SARS-CoV-2 in Humans

X. Xue, J. Shi, H. Xu, Y. Qin, Z. Yang, S. Feng, D. Liu, L. Jian, L. Hua, Y. Wang, Q. Zhang, X. Huang, X. Zhang, X. Li, C. Chen, , J. Liu

The paper predicts the binding ability between SARS-CoV-2 spike protein and human ACE2, revealing adaptive mutations that enhance transmissibility in humans.

bioRxiv · Jun 25, 2020Microbiology

An optimised protocol for isolation of RNA through laser capture microdissection of leaf material

L. Hua, J. M. Hibberd

The paper describes an optimized protocol for RNA isolation from leaf cells using laser capture microdissection, improving RNA quality by modifying embedding and sectioning methods.

bioRxiv · May 22, 2019Plant Biology

DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA as Diagnostic Biomarkers for Human Cancers

W. Li, X. Zhang, X. Lu, L. You, Y. Song, Z. Luo, J. Zhang, J. Nie, W. Zheng, D. Xu, Y. Wang, Y. Dong, S. Yu, J. Hong, J. Shi, , J. Liu

The paper identifies 5hmC signatures in cfDNA as accurate biomarkers for detecting colorectal and gastric cancers, outperforming conventional markers and matching tissue biopsy results.

Cell Research · Sep 19, 2017Peer-reviewedCancer Biology