Author

Laura Pontano Vaites

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Edward L. HuttliniD· 2 shared J. Wade HarperiD· 2 shared João A. PauloiD· 2 shared Steven P. GygiiD· 2 shared Tian ZhangiD· 2 shared Adriana PiteaiD· 1 shared Alessandro PalmaiD· 1 shared Alessia LoffredaiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersSystems Biology

Edward L. HuttlinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ribosome Quality Control Mitigates Proteotoxic Stress in Aneuploid Cells

Sonia Viganò, Marica Rosaria Ippolito, Simone Scorzoni, Lara Barrio, Alessia Loffreda, Marina Rodriguez‐Muñoz, Deborah Donzel, Yonatan Eliezer, Laura Pontano Vaites, João A. Paulo, Mattia Marenda, Alessandro Palma, Uri Ben‐David, Gabriella Viero, Marco Milán, Stefano Santaguida

The paper shows that ribosome quality control via ZNF598 degradation helps aneuploid cells survive proteotoxic stress, with ZNF598 expression linked to tumor aneuploidy.

bioRxiv · Jan 20, 2026 · PreprintCell Biology

Mapping cell structure across scales by fusing protein images and interactions

Yue Qin, Edward L. Huttlin, Casper F. Winsnes, Maya L. Gosztyla, Ludivine Wacheul, Marcus R. Kelly, Steven M. Blue, Fan Zheng, Michael Chen, Leah V. Schaffer, Katherine Licon, Anna Bäckström, Laura Pontano Vaites, John J. Y. Lee, Wei Ouyang, , Trey E. Ideker

The paper integrates protein imaging and interaction data to create a unified map of eukaryotic cell structure, revealing new subcellular systems and protein associations.

Nature · Nov 24, 2021Peer-reviewedSystems Biology

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, José Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra M. Thornock, Gabriela Zárraga-Granados, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, , Steven P. Gygi

The paper creates two large-scale cell-line-specific human interactomes using affinity-purification mass spectrometry and identifies shared and cell-specific protein interactions.

Cell · May 1, 2021Peer-reviewedSystems Biology