Author

Lesley Gilbert

University of York

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Sally R. JamesiD· 5 shared Grant M. Calder· 2 shared Helen M. AshwiniD· 2 shared Karen HoggiD· 2 shared Paul Martin KayeiD· 2 shared Shoumit DeyiD· 2 shared Adam DowleiD· 1 shared Alastair DroopiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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5 shared papersImmunology

Sally R. JamesORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Ontogeny-independent expression of LPCAT2 in granuloma macrophages during experimental visceral leishmaniasis

Shoumit Dey, Jianhua Cao, Benjamin Balluff, Gaia Mazza, Helen M. Ashwin, Lesley Gilbert, Sally R. James, Adam Dowle, Grant M. Calder, Nidhi Sharma Dey, Peter J O’Toole, Ron M. A. Heeren, Paul Martin Kaye

The paper uses multimodal imaging and single-cell transcriptomics to identify LPCAT2-mediated membrane remodeling in granuloma macrophages during visceral leishmaniasis.

Communications Biology · Mar 20, 2026Peer-reviewedImmunology

Bi-directional highways and super-seeder tissues underpin parasite dissemination in experimental visceral leishmaniasis.

Ciara F. Loughrey, Juliana B. T. Carnielli, Shoumit Dey, Helen M. Ashwin, Sally R. James, Lesley Gilbert, Samantha L. Donninger, Alastair Droop, Grant M. Calder, Karen Hogg, Jon W. Pitchford, Jeremy Charles Mottram, Paul Martin Kaye

This study maps parasite dissemination patterns in visceral leishmaniasis using a barcoded library and ecological analysis, revealing bi-directional highways and super-seeder tissues.

bioRxiv · Dec 30, 2025 · PreprintMicrobiology

An ERα-Dependent Hypoxia Response Defines EMT-Adjacent Tumour Regions and Suppresses the Pro-survival Effects of Amiloride in Estrogen Receptor-Positive Breast Cancer

Jodie R. Malcolm, Jack Stenning, Jacob Pope, Jakub Lukaszonek, Susanna F Rose, Taylor E. Smith, Lesley Gilbert, Sally R. James, Katherine S. Bridge, William J. Brackenbury, Andrew N. Holding

The paper identifies an ERα-dependent hypoxia response in ER+ breast cancer that influences gene expression and sensitivity to amiloride, linking hypoxia and ER signaling.

bioRxiv · Oct 3, 2025 · PreprintCancer Biology

Assembly and annotation of Solanum dulcamara and Solanum nigrum plant genomes, two nightshades with different susceptibilities to Ralstonia solanacearum

Sara Franco Ortega, Sally R. James, Lesley Gilbert, Karen Hogg, Harry Stevens, Jason Daff, Ville‐Petri Friman, Andrea L. Harper

The paper assembles and annotates the genomes of two nightshade plants, S. dulcamara and S. nigrum, to identify genetic differences associated with resistance and susceptibility to Ralstonia solanacearum.

bioRxiv · Feb 12, 2025 · PreprintPlant Biology

The rhythmic transcriptional landscape in Caenorhabditis elegans: daily, circadian and novel 16-hour cycling gene expression revealed by RNA-sequencing

Jack Munns, Katherine Newling, Sally R. James, Lesley Gilbert, Seth J Davis, Sangeeta Chawla

This study identifies daily and 16-hour gene expression rhythms in C. elegans using RNA-seq, revealing both circadian and novel oscillatory patterns.

bioRxiv · Jul 6, 2024 · PreprintPhysiology