Author

Liwen Ma

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:CRISPR screen· 1 Approach:statistical model· 1

Frequent Co-Authors

Hugo Jozef BelleniD· 3 shared Oguz KancaiD· 3 shared Jonathan D. ZiriniD· 2 shared Ming Jian Ge· 2 shared Norbert PerrimoniD· 2 shared Wen‐Wen LiniD· 2 shared Yanhui HuiD· 2 shared Zhongyuan ZuoiD· 2 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersGenetics

Hugo Jozef BellenORCID

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3 papers

Recent·Most cited

Revealing the nervous system requirements of Alzheimer disease risk genes in Drosophila

Jennifer Deger, Shabab B. Hannan, Mingxue Gu, Colleen E Strohlein, Lindsey D. Goodman, Sasidhar Pasupuleti, Zahid Shaik, Liwen Ma, Yarong Li, Jiayang Li, Morgan C Stephens, Michal Tyrlík, Zhandong Liu, Ismael Al‐Ramahi, Juan Botas, , Joshua M Shulman

This study identifies nervous system requirements for Alzheimer's disease risk genes in Drosophila by analyzing gene function and neurodegeneration.

bioRxiv · Jul 24, 2025 · PreprintGenetics

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR mediated homologous recombination

Oguz Kanca, Jonathan D. Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen‐Wen Lin, Liwen Ma, Ming Jian Ge, Zhongyuan Zuo, Luping Liu, Robert W. Levis, Norbert Perrimon, Hugo Jozef Bellen

The paper develops new CRISPR-based constructs for Drosophila gene tagging, enabling efficient gene modification with a 70-80% success rate regardless of exon-intron structure.

eLife · Jun 20, 2022Peer-reviewedGenetics

An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms

Oguz Kanca, Jonathan D. Zirin, Jorge García‐Marqués, Shannon M. Knight, Donghui Yang‐Zhou, Gabriel O. Amador, Hyung-Lok Chung, Zhongyuan Zuo, Liwen Ma, Yuchun He, Wen‐Wen Lin, Yīng Fāng, Ming Jian Ge, Shinya Yamamoto, Karen L. Schulze, , Hugo Jozef Bellen

The paper introduces three simplified CRISPR-based methods for DNA insertion in Drosophila, using short homology arms and ssDNA/dsDNA donors to generate transgenic constructs efficiently.

eLife · Nov 1, 2019Peer-reviewedGenomics