Author

Lynsay MacLaren

Whitman-Walker Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Talia M. MotaiD· 2 shared Yanqin ReniD· 2 shared Adam R. WardiD· 1 shared Alberto BosqueiD· 1 shared Ali DaneshiD· 1 shared Andrea GramaticaiD· 1 shared Andrew P. KurlandiD· 1 shared Andrew Wilson· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Talia M. MotaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8+ T-cell revitalization

Andrea Gramatica, Itzayana G. Miller, Adam R. Ward, Khan Farzana, Tyler J. Kemmer, Jared Weiler, Tan Thinh Huynh, Paul Zumbo, Andrew P. Kurland, Louise Leyre, Yanqin Ren, Thaís Klevorn, Dennis C. Copertino, Uchenna K. Chukwukere, Callie Levinger, , R. Brad Jones

The paper shows that tazemetostat reduces HIV reservoirs and improves CD8+ T-cell function by increasing MHC-I expression and promoting anti-HIV immune responses.

Cell Reports · May 1, 2025Peer-reviewedImmunology

HIV Diversity Considerations in the Application of the Intact Proviral DNA Assay (IPDA)

Natalie N. Kinloch, Yanqin Ren, Winiffer D. Conce Alberto, Winnie W. Y. Dong, Pragya Khadka, Szu-Han Huang, Talia M. Mota, Andrew Wilson, Aniqa Shahid, Don Kirkby, Marianne Harris, Colin M Kovacs, Erika Benko, Mario Ostrowski, Perla M. Del Río Estrada, , Richard Brad Jones

The paper evaluates the Intact Proviral DNA Assay (IPDA) for HIV reservoir quantification, finding that HIV diversity leads to a 28% failure rate and underestimation of reservoir size.

Nature Communications · Jan 8, 2021Peer-reviewedGenetics