M. Gomez

Development of a robotic cluster for automated and scalable cell therapy manufacturing

This paper develops a robotic system to automate cell therapy manufacturing, demonstrating comparable results to manual methods in expanding human CD8+ T cells.

Dissociable contributions of basolateral amygdala and ventrolateral orbitofrontal cortex to flexible learning under uncertainty

This study investigates the distinct roles of vlOFC and BLA in stimulus- and action-based reversal learning under uncertainty using chemogenetic inhibition in rats.

Failed reprogramming of transformed cells due to induction of apoptosis and senescence impairs tumor progression in lung cancer

The paper shows that OSKM expression in lung cancer cells induces apoptosis and senescence, limiting tumor growth and reducing tumor burden in vivo.

Programmable delivery of fluoxetine via wearable bioelectronics for wound healing in vivo

This paper introduces a wearable bioelectronic bandage that delivers fluoxetine on-demand to wounds, reducing inflammation and accelerating healing in mice.

A Low-Cost Stage-Top Incubation Device For Human Cell Imaging Using Rapid Prototyping Methods

This paper describes a low-cost DIY stage-top incubation device for human cell imaging using 3D printing and SBCs, reducing costs by 100x compared to commercial alternatives.

A data-driven approach to establishing cell motility patterns as predictors of macrophage subtypes and their relation to cell morphology

This paper shows that macrophage motility patterns and morphology can predict their subtypes, with combined features improving prediction accuracy to 75%.

Male harm suppresses female fitness to affect the dynamics of adaptation and evolutionary rescue

This paper quantifies the negative impact of male harm on female fitness across taxa and shows how sexual conflict affects adaptation and evolutionary rescue in response to environmental change.

The structure of insulin granule core determines secretory capacity being reduced in type-2 diabetes

The paper investigates the structure of insulin granule cores and shows that their size reduction in type-2 diabetes correlates with impaired insulin secretion.

Screening of Cultivars for Tissue Culture Response and Establishment of Genetic Transformation in a High-yielding and Disease-resistant Cultivar of Theobroma cacao

The paper establishes tissue culture and genetic transformation methods for a high-yielding, disease-resistant Theobroma cacao cultivar and identifies factors improving T-DNA delivery and somatic embryogenesis.

Peripheral Natural Killer cells from chronic hepatitis B patients display molecular hallmarks of T cell exhaustion

The paper identifies molecular similarities between NK cells from chronic hepatitis B patients and exhausted T cells, highlighting shared pathways like TOX and NFAT in their dysfunction.

PARASITES MEDIATE CONDITION-DEPENDENT SEXUAL SELECTION FOR LOCAL ADAPTATION IN A NATURAL INSECT POPULATION

The paper quantifies parasite-mediated sexual selection in a natural insect population and shows increased local adaptation against parasites over time.

Evolution of Replication Origins in Vertebrate Genomes: Rapid Turnover Despite Selective Constraints.

The paper compares replication origin maps across vertebrates to study their evolutionary dynamics and functional constraints, finding rapid turnover despite some genetic constraints.