Author

M. J. McDonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Assay:whole-genome sequencing· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. C. Woods· 2 shared M. M. Desai· 2 shared A. M. Kunjapur· 1 shared A. M. Phillips· 1 shared A. Moulana· 1 shared A. N. Nguyen Ba· 1 shared A. Neild· 1 shared A. Rego-Costa· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

L. C. Woods

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bacteriophage adaptation to a mammalian mucosa reveals a trans-domain evolutionary axis

W. H. Chin, C. Kett, O. Cooper, D. Müseler, Y. Zhang, R. S. Bamert, R. Patwa, L. C. Woods, C. Devendran, J. Tiralongo, T. Lithgow, M. J. McDonald, A. Neild, J. J. Barr

This study shows that bacteriophages adapt to the mammalian gut mucosa through mutations and recombination, gaining a fitness advantage by altering their binding to mucin glycans.

bioRxiv · May 11, 2021 · PreprintMicrobiology

Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations

M. S. Johnson, S. Gopalakrishnan, J. Goyal, M. E. Dillingham, C. W. Bakerlee, P. T. Humphrey, T. Jagdish, E. R. Jerison, K. Kosheleva, K. R. Lawrence, J. Min, A. Moulana, A. M. Phillips, J. C. Piper, R. Purkanti, , M. M. Desai

This study tracks phenotypic and molecular evolution in 205 yeast populations over 10,000 generations, revealing patterns of declining adaptability, mutation accumulation, and genetic parallelism.

bioRxiv · Oct 9, 2020Evolutionary Biology

Alternative hydrogen uptake pathways suppress methane production in ruminants

C. Greening, R. Geier, C. Wang, L. C. Woods, S. E. Morales, M. J. McDonald, R. Rushton-Green, X. C. Morgan, S. Koike, S. C. Leahy, W. J. Kelly, I. Cann, G. T. Attwood, G. M. Cook, R. I. Mackie

This study identifies alternative hydrogen uptake pathways in ruminants that reduce methane production by competing with methanogens for hydrogen.

bioRxiv · Dec 4, 2018 · PreprintMicrobiology

Long-term adaptive evolution of genomically recoded Escherichia coli

T. M. Wannier, A. M. Kunjapur, D. P. Rice, M. J. McDonald, M. M. Desai, G. M. Church

This paper reports the adaptive evolution of a genomically recoded E. coli strain to improve its fitness and identifies mutations that enhance its growth in defined media.

Proceedings of the National Academy of Sciences · Feb 13, 2018Peer-reviewedEvolutionary Biology